Figure 1

Schematic diagrams of the experimental group design and protocol for chicken ovalbumin (OVA)-induced allergic asthma. (A) Female BALB/c mice were divided into PBS, OVA, and PS-F2 groups (n = 10) which received different immunizations and treatments as indicated. (B) Mice were immunized with OVA + alum or PBS on days 0, 10, and 20. Mice also received treatment with PS-F2 or PBS on the indicated days. All animals were challenged i.n. with OVA on day 27. Twenty-four hours after OVA challenge, airway hyperresponsiveness (AHR) was measured, mice were sacrificed, and serum, bronchoalveolar lavage fluid (BALF), and lung tissue samples were collected for further analysis.