Figure 4

Effects of pentoxifylline (PTX) on fructosamine levels (A) and glycated hemoglobin (B) in diabetic rats, after 1- or 2-month treatments. The values are means ± SEM from 6 to 14 animals per group. A - DC vs. GLI5: ***q = 6.493; vs. PTX50: ***q = 6.374; vs. PTX5: *q = 3.984; vs. GLI2: *q = 3.827; vs. PTX5 + GLI2: ***q = 8.148; vs. GLI5: ***q = 6.493; PTX5 + GLI2 vs. PTX5: *q = 4.013. B - DC vs. PTX50: ***q = 9.118; vs. PTX5: ***q = 7.677; vs. GLI2: ***q = 7.062; vs. PTX5 + GLI2: ***q = 12.32; PTX5 + GLI2 vs. GLI2: ***q = 6.265; vs. PTX5: ***q = 6.505 (One-way ANOVA, followed by Newman-Keuls as the post hoc test). DC = untreated diabetic controls; GLI = glibenclamide.