Figure 3

Effects of pentoxifylline (PTX) on DZD-induced hypoglycemia, in diabetic (A) and non-diabetic (B) rats. The values are means ± SEM from 6 animals per group. The animals were administered with DZD (250 mg/kg, i.p.). Blood was collected immediately after DZD administration (0 h) and at 1 and 2 h later. DC = untreated diabetic control; DZD = diazoxide. A - DC vs. PTX50 + DZD, 0 h: **q = 5.778; 1 h: *q = 4.943; 2 h: **q = 5.130; DC vs. GLI5 + DZD, 0 h: **q = 5.568; 1 h: *q = 4.267; 2 h: **q = 5.941 (One-way ANOVA, followed by Newman-Keuls as the post-hoc test). B - **p < 0.05 vs. the same group, at 1 and 2 h after DZD administration (paired Student t test).