Figure 2

Effects of a low dose (5 mg/kg, p.o.) of pentoxifylline (PTX), alone or combined to glibenclamide (GLI, 2 mg/kg, p.o.) or metformin (MET, 5 mg/kg, p.o.), on glycemia (A) and TG (B) levels, after 1-week treatment of diabetic rats. The values are means ± SEM from 5–15 animals per group. PTX5A vs. PTX5B: *p < 0.0443; PTX5A + GLI2A vs. PTX5A: *p < 0.0322; MET5A vs. MET5B: **p < 0.0026. Data analyzed by the paired Student t test. All comparisons were done after (A) vs. before (B) treatments, in each group.