Figure 1

Two pathways contribute to C. elegans resistance against P. luminescens . (A) pmk-1- knocked down C. elegans decreased resistance against P. luminescens (P < 0.005). (B) daf-16-knocked down did not affect C. elegans resistance against P. luminescens (P > 0.05). (C) daf-2-knocked down C. elegans increased resistance against P. luminescens (P < 0.005). (D) Null mutation of daf-16 did not affect C. elegans lifespan (P > 0.05), and knockdown of daf-2 didn’t affect daf-16 null mutant (P > 0.05). Survival curves are presented based on three or two trials (see Table 1). P values were calculated by log-rank test compared with the blank(RNAi).