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Table 2 Mean ± SD of thyrotropin (TSH), thyroid hormones, serum iodine, and cardio-metabolic variables in euthyroid post-menopausal women grouped according to the presence of metabolic syndrome (MetS) and triiodothyronine (T3) concentration

From: Association between the serum concentration of triiodothyronine with components of metabolic syndrome, cardiovascular risk, and diet in euthyroid post-menopausal women without and with metabolic syndrome

  Without MetS MetS-T3Q1 MetS-T3Q2 MetS-T3Q3 MetS-T3Q4 Statistic K or F; P
n = 33 n = 22 n = 21 n =21 n = 23
TSH (μUI/mL) 2.8 ± 2.1a 2.5 ± 1.4a 2.3 ± 1.5a 2.6 ± 1.9a 2.4 ± 1.8a Ns
T4 (μg/mL) 8.9 ± 0.4ab 8.2 ± 1.1b 8.4 ± 1.5ab 9.7 ± 1.1a 9.4 ± 1.2a 4.0; 0.002
Free T4 (μg/mL) 1.1 ± 0.2 1.1 ± 0.1 1.1 ± 0.1 1.1 ± 0.2 1.1 ± 0.1 Ns
T3 (μg/mL) 1.2 ± 0.2ac 0.9 ± 0.1b 1.1 ± 0.04a 1.2 ± 0.06c 1.4 ± 0.1d 62.9; <0.0001
Range of T3 concentration (μg/mL) (0.81-1.47) (0.66-0.99) (0.10-1.13) (1.14-1.33) (1.34-1.70)  
Age (years) 67.4 ± 11.8 70.8 ± 8.6 68.9 ± 10.4 66.3 ± 7.5 64.9 ± 10.5 Ns
BMI (kg/m2) 25.1 ± 5.3a 24.4 ± 3.8a 26.6 ± 3.5ab 26.8 ± 3.0ab 28.6 ± 5.0b 14.9; 0.004
Glucose (mg/dL) 100.6 ± 30.6a 133.7 ± 47.5bc 158.0 ± 58.9c 135.5 ± 56.0bc 109.7 ± 57.5ab 28.5; <0.0001
Insulin (μUI/mL) 9.2 ± 5.8a 8.8 ± 8.6a 10.0 ± 6.5a 12.6 ± 6.6ab 16.4 ± 7.0b 27.1; <0.0001
HOMA-IR 2.2 ± 1.4a 3.1 ± 3.4ab 3.6 ± 1.8abc 4.3 ± 3.0bc 4.4 ± 2.0c 25.5; <0.0001
HDL-C (mg/dL) 51.0 ± 19.3a 44.4 ± 9.6ab 48.7 ± 30.0ab 40.1 ± 6.0b 39.7 ± 10.0ab 12.0; 0.01
Cholesterol (mg/dL) 198.5 ± 6.2 215.5 ± 13.6 197.9 ± 8.5 183.8 ± 9.3 195.6 ± 7.7 Ns
Systolic pressure (mmHg) 118.2 ± 3.1a 125.5 ± 3.2ab 133.3 ± 3.9b 124.3 ± 2.9ab 129.6 ± 2.9ab 12.3; 0.01
Diastolic pressure (mmHg) 73.6 ± 1.6 73.1 ± 1.5 73.3 ± 2.4 74.7 ± 2.4 75.7 ± 1.8 Ns
  1. T4, thyroxine; BMI, body mass index; HOMA-IR, insulin resistance index; high-density lipoprotein cholesterol (HDL-C). ANOVA or Kruskal-Wallis tests and Tukey-Kramer or Dunns post-hoc test were applied. Ns: no significant. Different letters indicate statistical differences between groups reported by post-hoc tests.