Skip to main content

Table 2 Mean ± SD of thyrotropin (TSH), thyroid hormones, serum iodine, and cardio-metabolic variables in euthyroid post-menopausal women grouped according to the presence of metabolic syndrome (MetS) and triiodothyronine (T3) concentration

From: Association between the serum concentration of triiodothyronine with components of metabolic syndrome, cardiovascular risk, and diet in euthyroid post-menopausal women without and with metabolic syndrome

 

Without MetS

MetS-T3Q1

MetS-T3Q2

MetS-T3Q3

MetS-T3Q4

Statistic K or F; P

n = 33

n = 22

n = 21

n =21

n = 23

TSH (μUI/mL)

2.8 ± 2.1a

2.5 ± 1.4a

2.3 ± 1.5a

2.6 ± 1.9a

2.4 ± 1.8a

Ns

T4 (μg/mL)

8.9 ± 0.4ab

8.2 ± 1.1b

8.4 ± 1.5ab

9.7 ± 1.1a

9.4 ± 1.2a

4.0; 0.002

Free T4 (μg/mL)

1.1 ± 0.2

1.1 ± 0.1

1.1 ± 0.1

1.1 ± 0.2

1.1 ± 0.1

Ns

T3 (μg/mL)

1.2 ± 0.2ac

0.9 ± 0.1b

1.1 ± 0.04a

1.2 ± 0.06c

1.4 ± 0.1d

62.9; <0.0001

Range of T3 concentration (μg/mL)

(0.81-1.47)

(0.66-0.99)

(0.10-1.13)

(1.14-1.33)

(1.34-1.70)

 

Age (years)

67.4 ± 11.8

70.8 ± 8.6

68.9 ± 10.4

66.3 ± 7.5

64.9 ± 10.5

Ns

BMI (kg/m2)

25.1 ± 5.3a

24.4 ± 3.8a

26.6 ± 3.5ab

26.8 ± 3.0ab

28.6 ± 5.0b

14.9; 0.004

Glucose (mg/dL)

100.6 ± 30.6a

133.7 ± 47.5bc

158.0 ± 58.9c

135.5 ± 56.0bc

109.7 ± 57.5ab

28.5; <0.0001

Insulin (μUI/mL)

9.2 ± 5.8a

8.8 ± 8.6a

10.0 ± 6.5a

12.6 ± 6.6ab

16.4 ± 7.0b

27.1; <0.0001

HOMA-IR

2.2 ± 1.4a

3.1 ± 3.4ab

3.6 ± 1.8abc

4.3 ± 3.0bc

4.4 ± 2.0c

25.5; <0.0001

HDL-C (mg/dL)

51.0 ± 19.3a

44.4 ± 9.6ab

48.7 ± 30.0ab

40.1 ± 6.0b

39.7 ± 10.0ab

12.0; 0.01

Cholesterol (mg/dL)

198.5 ± 6.2

215.5 ± 13.6

197.9 ± 8.5

183.8 ± 9.3

195.6 ± 7.7

Ns

Systolic pressure (mmHg)

118.2 ± 3.1a

125.5 ± 3.2ab

133.3 ± 3.9b

124.3 ± 2.9ab

129.6 ± 2.9ab

12.3; 0.01

Diastolic pressure (mmHg)

73.6 ± 1.6

73.1 ± 1.5

73.3 ± 2.4

74.7 ± 2.4

75.7 ± 1.8

Ns

  1. T4, thyroxine; BMI, body mass index; HOMA-IR, insulin resistance index; high-density lipoprotein cholesterol (HDL-C). ANOVA or Kruskal-Wallis tests and Tukey-Kramer or Dunns post-hoc test were applied. Ns: no significant. Different letters indicate statistical differences between groups reported by post-hoc tests.