Figure 2

A-CPreoperative alcohol consumption in relation to early events, including local or regional recurrence, new breast cancer, or distant metastases, in:A) All patients – adjusted HR 0.55 (95% CI 0.34-0.91) for 1-3 drinks/week, adjusted HR 0.90 (95% CI 0.55-1.48) for 4-9 drinks/week, and adjusted HR 0.71 (95% CI 0.21-2.32) for 10+ drinks/week. Adjusted HR for any alcohol consumption: 0.69 (95% CI 0.45-1.04). B) Patients with axillary lymph node involvement. – adjusted HR 0.38 (95% CI 0.19-0.77) for 1-3 drinks/week, adjusted HR 0.52 (95% CI 0.25-1.07) for 4-9 drinks/week, and adjusted HR 0.33 (95% CI 0.04-2.55) for 10+ drinks/week. There were no events in the group with 10+ drinks/week. Adjusted HR for any alcohol consumption: 0.43 (95% CI 0.24-0.77). C) Patients without axillary lymph node involvement – adjusted HR 0.93 (95% CI 0.44-1.94) for 1-3 drinks/week, adjusted HR 1.81 (95% CI 0.87-3.75) for 4-9 drinks/week, and adjusted HR 1.28 (95% CI 0.28-5.82) for 10+ drinks/week. Adjusted HR for any alcohol consumption: 1.24 (95% CI 0.66-2.34). Since this is an on-going cohort, the number of patients decreases as the follow-up time increases.