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Table 3 Regression estimated average incremental monthly costs by adverse event count ‡

From: Identification and cost of adverse events in metastatic breast cancer in taxane and capecitabine based regimens

 

1st Line Taxane

1st Line Capecitabine

2nd Line Taxane

2nd Line Capecitabine

With any adverse event, $

    

Chemotherapy costs

$478**

$630*

$513**

$118

Other medication costs

-$5

$176*

-$54*

$139*

Hospitalization costs

$920**

$1,745*

$441**

$2,771*

Emergency department costs

$29

$43*

$17

$91*

Outpatient services costs

-$280**

-$777*

$531*

$1,319

Total costs

$1,142**

$1,817*

$1,448**

$4,437*

With 1–2 adverse events, $

    

Chemotherapy costs

$342*

$75

$22

$1

Other medication costs

-$3

$151*

-$13

$52

Hospitalization costs

$169

$755

$57

$1,018

Emergency department costs

-$6

$25

$23

$34

Outpatient services costs

-$226*

-$903*

$154

-$19

Total costs

$276

$104

$243

$1,087

With 3–4 adverse events, $

    

Chemotherapy costs

$549*

$551

$325*

-$283

Other medication costs

$14

$220*

-$101*

$260*

Hospitalization costs

$296

$1,648

$183

$1,221

Emergency department costs

-$12

$50

-$3

$174*

Outpatient services costs

-$182

-$817

$1,103**

$693

Total costs

$667*

$1,652

$1,506**

$2,065

With greater than 4 adverse events, $

 

Chemotherapy costs

$488*

$1,537**

$1,053**

$535

Other medication costs

-$17

$192*

-$71*

$191*

Hospitalization costs

$1,389**

$3,393**

$934**

$5,777**

Emergency department costs

$54*

$67*

$24

$128*

Outpatient services costs

-$353**

-$555

$593*

$3,323*

Total costs

$1,562**

$4,635**

$2,533**

$9,954**

  1. ‡Relative to those with no adverse events and adjusted for age (linear) and Charlson Comorbidity Index (categorized 0, 1, 2, and 3+), *p < 0.05, **p < 0.0001.