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Table 3 Characteristics of patients and monitoring of viral load in those receiving preemptive or therapeutic antiviral treatment

From: Prospective, comprehensive, and effective viral monitoring in Cuban children undergoing solid organ transplantation

No patient

Type of transplant

Therapy

Weeks of follow-up at beginning therapy (duration in weeks)

Signs and symptoms

Viral load (copies/mL) before therapy

Viral load (copies/mL) after therapy

1

Liver

Valganciclovir

14 (4)

asymptomatic

CMV viremia: 103

No viremia

8

Liver

Valganciclovir

11 (4)

asymptomatic

CMV viremia: 104

No viremia

22

Liver

Valganciclovir

10 (10)

Elevated AST, ALT

Viremia: CMV 104, EBV 10

No viremia

23

Liver

Ganciclovir + Valganciclovir

5 (5 days + 4)

Elevated AST, ALT

Viremia: CMV 104

No viremia

Urine: CMV 103

Urine: no virus detected

12

Kidney

Valganciclovir

29 (4)

asymptomatic

Viremia: CMV 10, BKV 10

No viremia

Urine: CMV 102, BKV 107

Urine: CMV 10, BKV 104

15

Kidney

Valganciclovir

22 (4)

Fever

Viremia: CMV 102

No viremia

Urine: CMV 105

Urine: no virus detected

34 (12)

Fever and chronic reject

Viremia: CMV 102

No viremia

Urine: CMV 106

Urine: CMV 105

18

Kidney

Valganciclovir

13 (12)

Urinary infection

Viremia: CMV 102

No viremia

Urine: CMV 103, BKV 102

Urine: CMV 102

  1. Abbreviations: AST: aspartate aminotransferase, ALT: alanine aminotransferase, CMV: Cytomegalovirus, EBV: Epstein-Barr virus, BKV: BK virus.