Table 2 Prognostic factors associated with poor cancer-specific survival
Factors | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
HR | 95% CI | p-value | HR | 95% CI | p-value | |
Age (cont.) | 1.004 | 0.980 ~ 1.028 | 0.762 | - | - | - |
Gender (%) | ||||||
Male | Reference | - | - | - | ||
Female | 1.087 | 0.574 ~ 2.059 | 0.797 | - | - | - |
BMI (kg/m2) (cont.) | 0.891 | 0.812 ~ 0.979 | 0.016 | 0.884 | 0.668 ~ 0.924 | 0.031 |
ECOG performance status (%) | ||||||
0 | Reference | - | - | - | ||
1 | 1.576 | 0.907 ~ 2.807 | 0.105 | - | - | - |
2 | 1.598 | 0.879 ~ 5.131 | 0.457 | - | - | - |
MSKCC risk group (%) | ||||||
Good | Reference | Reference | ||||
Intermediate | 2.743 | 1.444 ~ 5.212 | 0.002 | 2.841 | 1.191 ~ 6.777 | 0.019 |
Poor | 10.155 | 2.168 ~ 47.569 | 0.003 | 7.503 | 1.282 ~ 40.904 | 0.025 |
Synchronous metastasis (%) | 1.855 | 1.093 ~ 3.146 | 0.022 | 1.598 | 0.783 ~ 3.260 | 0.197 |
Multiple organ metastasis (%) | 1.769 | 1.033 ~ 3.029 | 0.038 | 1.237 | 0.624 ~ 1.736 | 0.789 |
Hemoglobin (g/dℓ) < reference value | 0.672 | 0.565 ~ 0.800 | 0.001 | 0.756 | 0.595 ~ 0.959 | 0.021 |
Albumin ≥ 3.5 g/dℓ | 0.442 | 0.262 ~ 0.744 | 0.002 | 1.000 | 0.493 ~ 2.028 | 1.000 |
Corrected calcium ≥ 10.0 mg/dℓ | 1.352 | 1.090 ~ 1.677 | 0.006 | 1.132 | 0.876 ~ 1.462 | 0.345 |
Pre-treatment NLR ≤ 2.5 | 1.237 | 1.012 ~ 1.568 | 0.021 | 1.023 | 0.864 ~ 1.157 | 0.542 |
Post-treatment NLR ≤ 1.1 | 1.943 | 1.125 ~ 3.747 | 0.017 | 2.127 | 1.021 ~ 4.535 | 0.038 |