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Table 2 MRI features according to each intrinsic subtype

From: Magnetic resonance imaging features of breast cancer according to intrinsic subtypes: correlations with neoadjuvant chemotherapy effects

 

LA

n-LA

LB

n-LB

LH2

n-LH2

H2

n-H2

TN

n-TN

MRI findings

(n = 24)

(n = 92)

(n = 15)

(n = 101)

(n = 14)

(n = 102)

(n = 23)

(n = 93)

(n = 40)

(n = 76)

Mass margin

  Smooth

7(29)

52(57)

7(47)

52(51)

6(43)

53(52)

15(65)b

44(47)

24(60)

35(46)

  Irregular

17(71)a

40(43)

8(53)

49(49)

8(57)

49(48)

8(35)

49(53)

16(40)

41(54)

 

aP = .005

     

bP = .032

   

Intratumoral necrosis

  Presence

4(17)

17(18)

3(20)

18(18)

0(0)

21(21)

2(9)

19(20)

12(30)c

9(12)

  Absence

20(83)

75(82)

12(80)

83(82)

14(100)

81(79)

21(91)

74(80)

28(70)

67(88)

         

cP = .019

 

Tumor extension around mass

  Presence

17(71)

69(75)

7(47)

79(78)

10(71)

76(75)

21(91)e

65(70)

31(78)

55(72)

  Absence

7(29)

23(25)

8(53)d

22(22)

4(29)

26(25)

2(9)

28(30)

9(22)

21(28)

   

dP = .0047

   

eP = .009

   

Kinetic curve pattern

  Washout

5(21)

37(40)

8(53)

34(34)

5(36)

37(36)

14(61)

28(30)

10(25)

32(42)

  Plateau

14(58)

44(48)

6(40)

52(51)

8(57)

50(49)

6(26)

52(56)

24(60)

34(45)

  Persistent

5(21)

11(12)

1(7)

15(15)

1(7)

15(15)

3(13)

13(14)

6(15)

10(13)

  1. LA luminal A, n-LA non-luminal A, LB luminal B, n-LB non-luminal B, LH2 luminal-HER2, n-LH2 non-luminal-HER2, H2 HER2, n-H2 non-HER2, TN triple-negative, n-TN non-triple-negative.
  2. a,b,c,d,eIndicates statistical significance (P < .05).