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Table 2 Frequency of hypermethylation of tumor suppressor gene loci in urothelial bladder cancer samples

From: Promoter hypermethylation of tumor suppressor genes correlates with tumor grade and invasiveness in patients with urothelial bladder cancer

Tumor suppressor gene Low grade urothelial carcinoma of urinary bladder (TCC) n = 43 High grade urothelial carcinoma of urinary bladder (TCC) n = 33
RASSF1A 49% (21/43) 82% (27/33)
APC 51% (22/43) 97% (32/33)
MGMT 93% (41/43) 94% (31/33)
CDKN2A 19% (8/43) 24% (8/33)
CDKN2B 37% (16/43) 57% (19/33)