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Table 2 Frequency of hypermethylation of tumor suppressor gene loci in urothelial bladder cancer samples

From: Promoter hypermethylation of tumor suppressor genes correlates with tumor grade and invasiveness in patients with urothelial bladder cancer

Tumor suppressor gene

Low grade urothelial carcinoma of urinary bladder (TCC) n = 43

High grade urothelial carcinoma of urinary bladder (TCC) n = 33

RASSF1A

49% (21/43)

82% (27/33)

APC

51% (22/43)

97% (32/33)

MGMT

93% (41/43)

94% (31/33)

CDKN2A

19% (8/43)

24% (8/33)

CDKN2B

37% (16/43)

57% (19/33)