Comparison of intelligence, weight and height in children after general anesthesia with and without perioperative desaturation in non-cardiac surgery: a historical and concurrent follow-up study

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Table 4 Multivariate linear regression predictingthe normalized IQ score, standardized within IQ test from PD exposure (n = 206)

Variables	Multivariate
	Coefficient (95% CI)	p-value
Age-specific weight percentile at index GA	0.003 (−0.001, 0.007)	0.16
Mother’s education (ref = Tertiary education)		< 0.001
Secondary school	−0.34 (−0.67, −0.01)
Primary school	−0.38 (−0.83, 0.06)
Father’s education (ref = Tertiary education)		0.007
Secondary school	−0.43 (−0.75, −0.11)
Primary school	−0.35 (−0.78, 0.07)
Training by parents (ref = Regular)		0.007
Partial	−0.41 (−0.69, −0.13)
None	−1.0 (−1.84, −0.15)
Repeated GA (per time)	−0.04 (−0.08, −0.01)	0.01
Duration of GA (hours) (ref = <1)		0.37
1-3	0.07 (−0.28, 0.41)
> 3	−0.21 (−0.7, 0.27)
PD (ref = No-PRE)		0.57
Yes	−0.06 (−0.3, 0.19)
Severity of PD (ref = No-PRE)		0.56
Mild to moderate PD (SpO₂ 86-94)	0.02 (−0.27,0.31)
Severe PD (SpO₂ ≤ 85)	−0.16 (−0.49, 0.16)

p-value by F test statistic, GA; General anesthesia, IQ; Intellligence quotient, PD; Perioperative desaturation, PRE; Perioperative respiratory event, SpO₂; Oxygen saturation by pulse oximetry.