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Table 3 Dose modifying factors a for quiescent tumor cells relative to the total tumor cell populations

From: The dependency of compound biological effectiveness factors on the type and the concentration of administered neutron capture agents in boron neutron capture therapy

 

Treatment

 

<Net micronucleus frequency = 0.7>

γ-Rays only

1.85 (1.7-2.0)b

Neutrons only

1.05 (1.0-1.1)

BPAc (250 mg/kg)

1.5 (1.4-1.6)

BPA (500 mg/kg)

1.55 (1.45-1.65)

BPA (750 mg/kg)

1.6 (1.5-1.7)

BSHd (125 mg/kg)

1.2 (1.15-1.25)

BSH (250 mg/kg)

1.3 (1.2-1.4)

BSH (325 mg/kg)

1.4 (1.3-1.5)

  1. a; Radiation dose required to obtain the net normalized micronucleus frequency of 0.7 in the quiescent tumor cell population in relation to the radiation dose required to obtain a net normalized micronucleus frequency of 0.7 in total tumor cell population.
  2. b; 95% confidence limit.
  3. c; Boronophenylalanine-10B.
  4. d; Sodium mercaptododecaborate-10B.
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