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Figure 1

From: The dependency of compound biological effectiveness factors on the type and the concentration of administered neutron capture agents in boron neutron capture therapy

Figure 1

Time course of changes in 10B concentrations in the solid tumors (a) and blood collected from the hearts (b) of SCC VII tumor-bearing mice after subcutaneous administration of each 10B-carrier. Left panel of (a) shows time course of changes in tumors following administration of boronophenylalanine-10B at doses of 250 (●), 500 (▲), or 750 (■) mg·kg−1. Right panel of (a) shows time course of changes in tumors following administration of sodium mercaptododecaborate-10B at doses of 125 (●), 250 (▲), or 375 (■) mg·kg−1. (b) shows time course of changes in blood following administration of each 10B-carrier. Solid lines represent boronophenylalanine-10B at the doses of 250 (○), 500 (△), or 750 (□) mg·kg−1. Dotted lines represent sodium mercaptododecaborate-10B at doses of 125 (○), 250 (△), or 375 (□) mg·kg−1. Bars represent standard errors.

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