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Table 2 Adjusted odds ratio (OR) and 95% confidence intervals (CI) of diagnostic wait times by demographic and tumour characteristics for screen, interval and symptomatic detected breast cancers

From: Clinical and prognostic factors associated with diagnostic wait times by breast cancer detection method

 

Screen-detected (N = 1181)

 

Interval (N = 319)

 

Symptomatic (N = 406)

 

Characteristics

n (%)

ORa

n (%)

ORa

n (%)

ORa

Wait time

<=31 days

>31 days

(95% CI)

<=20 days

>20 days

(95% CI)

<=7 days

>7 days

(95% CI)

Overall

599(50.7)

582 (49.3)

 

159 (49.8)

160 (51.2)

 

207 (49.0)

199 (51.0)

 

Age at diagnosis a

         

 50-59

232 (38.7)

218 (37.5)

1.00 (reference)

70 (43.8)

52 (32.7)

1.00 (reference)

79 (38.2)

86 (43.2)

1.00 (reference)

 60-69

367 (61.3)

364 (62.5)

0.91(0.61-1.37)

90 (56.5)

107 (67.3)

0.55(0.24-1.21)

128 (61.8)

113 (56.8)

1.05(0.50-2.18)

Period of diagnosis a

         

 1995-1999

335 (55.9)

317 (54.5)

1.00 (reference)

79(49.4)

69 (43.4)

1.00 (reference)

121 (58.5)

125 (62.8)

1.00 (reference)

 2000-2003

264 (44.1)

265 (45.5)

0.73(0.46-1.14)

81(50.6)

90 (56.6)

1.72(0.73-4.07)

86 (41.6)

74 (37.2)

0.58(0.26-1.29)

Last screen a

         

 OBSP

206 (34.4)

221 (38.0)

1.00 (reference)

74 (46.3)

49 (30.8)

1.00 (reference)

--

--

--

 OHIP

393 (65.6)

361 (62.0)

0.87(0.69-1.13)

86 (53.8)

110 (69.2)

1.93(1.20-3.10)*

--

--

--

Treatment center region a

         

 South Central

269 (44.9)

261 (44.9)

1.00 (reference)

71 (44.4)

79 (49.7)

1.00 (reference)

98 (29.5)

95 (47.7)

1.00 (reference)

 South Eastern

160 (26.7)

137 (23.5)

0.86(0.65-1.16)

45 (28.1)

25 (15.7)

0.47(0.25-0.85)*

61 (29.5)

34 (17.1)

0.58(0.35-0.97)*

 South Western

111 (18.5)

108 (18.6)

0.99(0.72-1.36)

28 (17.5)

28 (17.6)

0.87(0.46-1.63)

34 (16.4)

37 (18.6)

1.17(0.68-2.02)

 Northern

59 (9.90)

76 (13.1)

1.29(0.88-1.89)

16 (10.0)

27 (16.9)

1.50(0.73-3.06)

14 (6.8)

33 (16.6)

2.52(1.26-5.03)*

Income quintiles a

         

 1

102 (17.1)

83 (14.3)

1.00 (reference)

22 (14.0)

21 (13.4)

1.00 (reference)

51 (25.0)

43 (22.1)

1.00 (reference)

 2

102 (17.1)

119 (20.5)

1.43 (0.96-2.11)

25 (15.9)

31 (19.8)

1.25(0.55-2.82)

35 (17.2)

36 (18.5)

1.24 (0.68-2.31)

 3

117 (19.6)

107 (18.5)

1.13 (0.76-1.66)

39 (24.8)

33 (21.0)

0.84 (0.39-1.83)

30 (14.7)

34 (17.4)

1.34 (0.71-2.54)

 4

115 (19.3)

131 (22.6)

1.40 (0.95-2.05)

27 (17.2)

24 (15.3)

0.86 (0.37-1.98)

44 (21.6)

34 (17.4)

0.89 (0.48-1.63)

 5

161 (27.0)

140 (24.1)

1.08 (0.75-1.56)

44 (27.5)

48 (30.6)

1.13 (0.54-2.37)

44 (21.6)

48 (24.6)

1.28 (0.72-2.27)

Community size a

         

 1 500 000+

150 (25.1)

208 (35.7)

1.00 (reference)

48 (30.0)

61 (38.4)

1.00 (reference)

68(32.8)

71 (36.0)

1.00 (reference)

 500 000–1 499 999

128 (21.4)

77 (13.2)

0.42(0.29-0.61)*

28 (17.5)

17 (10.7)

0.41(0.20-0.85)*

35 (16.9)

19 (9.55)

0.53(0.27-1.01)

 100 000–499 999

151 (25.2)

146 (25.1)

0.68(0.50-0.93)*

39 (24.4)

37 (23.3)

0.68(0.37-1.24)

34 (16.4)

44(22.1)

1.22(0.70-2.15)

 10 000 – 99 999

62 (10.4)

58 (9.97)

0.65(0.42-0.99)*

21 (13.1)

21 (13.2)

0.77(0.37-1.59)

29 (14.0)

32 (16.1)

1.08(0.59-1.97)

 <10 000

108 (18.0)

93 (16.0)

0.60(0.42-0.86)*

24 (15.0)

23 (14.5)

0.71(0.35-1.44)

41 (19.8)

33 (16.6)

0.78(0.45-1.40)

Biopsy type b

         

 FNA/Core

381(63.6)

237(40.7)

1.00 (reference)

110(68.8)

70(44.0)

1.00 (reference)

167(80.7)

92(46.2)

1.00 (reference)

 Open

218(36.4)

345(59.3)

2.76(2.14-3.56)*

50 (31.3)

89 (56.0)

2.56(1.50-4.35)*

41 (19.3)

107 (53.8)

5.56(3.33-9.30)**

Tumour size c

         

 <1.0

160 (27.4)

224 (39.2)

1.00 (reference)

30 (20.3)

54 (34.4)

1.00 (reference)

14 (7.54)

25 (13.7)

1.00 (reference)

 1.0-1.5

125 (21.4)

143 (25.0)

0.80(0.58-1.11)

28 (18.92)

33 (21.0)

0.73(0.35-1.13)

17 (9.14)

29 (15.9)

0.96(0.36-2.54)

 1.5-2.0

121 (20.7)

88 (15.4)

0.56(0.39-0.80)*

30 (20.3)

20 (12.7)

0.38(0.17-0.83)

27 (14.5)

35 (19.1)

0.84(0.33-2.12)

 >2.0

179 (30.6)

117 (20.5)

0.50(0.36-0.69)**

60 (40.5)

50 (31.9)

0.56(0.30-1.08)

128 (68.8)

94 (51.4)

0.49(0.22-1.05)

Stage at diagnosis c

         

 I

309 (53.5)

353 (64.2)

1.00 (reference)

65 (43.3)

85 (55.6)

1.00 (reference)

37 (19.1)

55 (28.4)

1.00 (reference)

 II

194 (33.6)

138 (25.1)

0.66(0.50-0.87)*

51 (34.0)

39 (25.5)

0.80(0.45-1.43)

81 (41.8)

78 (41.9)

0.66(0.37-1.18)

 III-IV

75 (13.0)

59 (10.7)

0.72(0.49-1.06)

34 (227)

29(19.0)

0.72(0.37-1.36)

76 (39.2)

53 (28.5)

0.46(0.25-0.85)*

Nodal status c

         

 Negative

386 (67.6)

393 (72.6)

1.00 (reference)

93 (64.6)

98(67.1)

1.00 (reference)

83 (49.7)

99 (55.3)

1.00 (reference)

 Positive

185 (32.4)

148 (27.4)

0.83 (0.63-1.08)

51 (35.4)

47 (32.4)

1.02(0.60-1.73)

84 (50.8)

80 (44.7)

0.79(0.48-1.27)

  1. amodels adjusted by: age at diagnosis (continuous) year of diagnosis (continuous).
  2. bmodels adjusted by: age at diagnosis (continuous); year diagnosis (continuous); treatment center (categorical) tumour size (continuous); income quintile (categorical).
  3. cmodels adjusted by: age at diagnosis (continuous); year diagnosis (continuous); treatment center (categorical); biopsy type at diagnosis (categorical); income quintile (categorical).
  4. *p < 0.05.
  5. **p < 0.0001.