What predicts negative effects of rheumatoid arthritis? A follow-up two years after diagnosis

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Table 3 Clinical data on patients 20–65 years who participated in this study on adaptation to newly diagnosed rheumatoid arthritis (n = 95)

Variable	PSP, baseline	PSP, 24 months	Diff within group	NPSP, baseline	NPSP, 24 months	Diff within group	Diff of Δ-values between groups	Diff at baseline	Diff at 24 months
	(n = 41)		p-values*	(n = 54)		p-values*	p-values*	p-values*	p-values*
Other important disease	16 (39%)			24 (45%)				0.54
DAS-28	5.67 (4.72–6.36)	3.30 (2.45–4.34)	<0.001	5.09 (49–5.66)	3.08 (2.18–3.86)	<0.001	0.39	0.023	0.26
HAQ	1.13 (0.75–1.50)	0.63 (0.38–1.00)	<0.001	1.00 (0.63–1.25)	0.25 (0.00–0.63)	<0.001	0.11	0.15	<0.001
Patient-reported global perceived disease activity score	64 (42–77)	37 (20–67)	<0.001	44 (24–67)	21 (7–49)	<0.001	0.62	0.0024	0.019
Patient-reported pain	62 (45–71)	29 (16–52)	<0.001	48.5 (28–66)	18 (5–50)	<0.001	0.89	0.028	0.011
Disease activity score (assessed by rheumatologist)	3.0 (3.0–4.0)	2.0 (1.3–2.0)	<0.001	3.0 (3.0–3.0)	2.0 (1.0–2.0)	<0.001	0.59	0.59	0.43

Results presented as medians (interquartile range). Comparing data at diagnosis (or at 6 months) with at 24 months (or at 18 months).
*P values analyzed within groups by Wilcoxon’s paired test, and between groups Mann–Whitney test.
PSP = Patients with psychosocial problems.
NPSP = Patients with no psychosocial problems.