Table 1 Clinical and histological characteristics of the various study groups
From: Methylene blue as an early diagnostic marker for oral precancer and cancer
Criteria | Group I | Group II | Group III |
|---|---|---|---|
Premalignant lesions (n = 50) | OSCC (n = 50) | Controls (n = 20) | |
Age ≤ 40 yrs | 28 56% | 8 16% | 12 60% |
  ≥40 yrs | 22 44% | 42 84% | 8 40% |
Sex Females | 2 4% | 14 28% | 4 20% |
  Males | 48 96% | 36 72% | 16 80% |
Site Buccal Mucosa(BM) | 40 leukoplakia | 44 BM with vest. ridge | ---- |
  Palate | 4 smoker’s palate | 2 | |
  Tongue | 2 leukoplakia | 2 | |
  Floor of mouth |  | 2 | |
Tobacco Use No | 0 | 0 | 20 |
  Yes | 50 | 50 | 0 |
Histological Diagnosis | Mild 10 20% | WDSCC 30 60% | --- |
Moderate 34 68% | MDSCC 16 32% | ||
Severe 2 4% | PDSCC 2 4 % | ||
Hyperkeratosis 4 8% | No evidence of 2 4% | ||
without dysplasia | Malignancy |