From: Outcomes of patients with acetaminophen-associated toxic hepatitis at a far east poison center
Variable | Total (N = 187) | No toxic hepatitis (N = 172) | Toxic hepatitis (N = 15) | P value |
---|---|---|---|---|
Vital signs | ||||
Systolic blood pressure (mmHg) | 120.8 ± 18.8 | 120.1 ± 17.8 | 127.9 ± 26.1 | 0.008** |
Diastolic blood pressure (mmHg) | 72.6 ± 13.3 | 72.3 ± 13.0 | 75.9 ± 16.0 | 0.301 |
Heart rate (beat per minute) | 82.1 ± 16.4 | 81.9 ± 16.1 | 83.4 ± 20.0 | 0.494 |
Body temperature (°C) | 36.8 ± 4.4 | 36.8 ± 4.6 | 36.9 ± 0.84 | 0.718 |
Urinary system | ||||
Acute renal failure, n (%) | 0 (0) | 0 (0) | 0 (0) | 1.000 |
Gastrointestinal system | ||||
Nausea and vomiting, n (%) | 81 (43.3) | 71 (41.2) | 10 (66.6) | 0.052 |
Neurologic system | ||||
Conscious disturbance, n (%) | 41 (21.9) | 38 (22.0) | 3 (20.0) | 0.575 |
Headache, n (%) | 8 (4.3) | 7 (4.1) | 1 (5.1) | 0.768 |
Seizure, n (%) | 2 (1.1) | 1 (0.01) | 1 (5.1) | 0.154 |
Respiratory system | ||||
Acute respiratory failure, n (%) | 7 (3.7) | 4 (2.3) | 3 (20.0) | 0.012* |