Table 1 Baseline characteristics of patients with acetaminophen poisoning (N = 187)
From: Outcomes of patients with acetaminophen-associated toxic hepatitis at a far east poison center
Variable | Total (N = 187) | No toxic hepatitis (N = 172) | Toxic hepatitis (N = 15) | P |
|---|---|---|---|---|
Serum acetaminophen (μg/mL) | 57.6 ± 60.3 | 114.4 ± 98.6 | 238.1 ± 300.0 | 0.007** |
Acetaminophen amount (tablet, 500 mg per tablet) | 37.1 ± 25.2 | 36.5 ± 25.1 | 44.2 ± 27.0 | 0.973 |
Age (years) | 28.9 ± 12.1 | 29.0 ± 12.4 | 28.4 ± 8.3 | 0.550 |
Male, n (%) | 35 (18.7) | 31 (18.0) | 4 (26.6) | 0.300 |
Time elapsed between acetaminophen ingestion and hospital arrival (hour) | 6.2 ± 6.0 | 5.4 ± 4.1 | 16.1 ± 13.5 | <0.001*** |
Hepatitis B virus carrier, n (%) | 10 (5.3) | 6 (3.5) | 4 (26.6) | <0.001*** |
Alcohol consumption, n (%) | 35 (18.7) | 32 (18.6) | 3 (20.0) | 0.599 |
Smoking habit, n (%) | 29 (15.5) | 26 (15.1) | 3 (20.0) | 0.420 |
Hypertension, n (%) | 6 (3.3) | 5 (2.9) | 1 (6.7) | 0.399 |
Diabetes mellitus, n (%) | 3 (1.6) | 3 (1.7) | 0 (0) | 0.777 |
Malignancy, n (%) | 3 (1.6) | 3 (1.7) | 0 (0) | 0.777 |
Depressive disorder, n (%) | 125 (66.8) | 114 (66.2) | 11 (73.3) | 0.404 |
Amphetamine abuse, n (%) | 1 (0.5) | 1 (0.7) | 0 (0) | 0.607 |
Ketamine abuse, n (%) | 2 (1.1) | 1 (0.7) | 0 (0) | 0.308 |
Heroin abuse, n (%) | 0 (0) | 0 (0) | 0 (0) | 1.000 |
Use of benzodiazepine hypnotics, n (%) | 40 (21.4) | 38 (22.1) | 2 (13.3) | 0.338 |