Table 2 The estimated posterior mean of parameters, the 95% CI, BIC values and the BMA weights for each of the models based on phenotype for the DLBCL dataset
From: Modelling survival data to account for model uncertainty: a single model or model averaging?
Phenotype | Model | Variable | Parameter | Mean | 95% CI | BIC | Weight |
|---|---|---|---|---|---|---|---|
GCB | Weibull | α | 0.692 | (0.5365, 0.8595) | 341.212 | 0.497 | |
Intercept | β 0 | -1.649 | (-2.185, -1.17) | ||||
GCB | β 1 | -0.179 | (-0.5859, 0.239) | ||||
Lymphoma | β 2 | -0.118 | (-0.3958, 0.1607) | ||||
Proliferation | β 3 | 0.459 | (-0.0306, 0.934) | ||||
BMP6 | β 4 | 0.414 | (0.01773, 0.809) | ||||
MHC | β 5 | -0.325 | (-0.6389, -0.01228) | ||||
Mixture | α 1 | 4.252 | (2.591, 7.175) | 377.759 | ≈0 | ||
α 2 | 0.816 | (0.6209, 1.032) | |||||
Intercept | β 01 | 6.491 | (5.246, 7.781) | ||||
β 02 | -2.152 | (-2.798, -1.567) | |||||
GCB | β 11 | -11.81 | (-13.05, -10.53) | ||||
β 12 | -0.030 | (-0.5104, 0.4592) | |||||
Lymphoma | β 21 | -1.839 | (-3.082, -0.6744) | ||||
β 22 | -0.134 | (-0.48, 0.2254) | |||||
Proliferation | β 31 | -2.165 | (-3.313, -0.9932) | ||||
β 32 | 0.588 | (-0.07796, 1.407) | |||||
BMP6 | β 41 | -0.242 | (-1.357, 0.8482) | ||||
β 42 | 0.654 | (0.17, 1.161) | |||||
MHC | β 51 | -0.629 | (-1.993, 0.5117) | ||||
β 52 | -0.382 | (-0.7687, -0.002227) | |||||
ϕ 1 | 0.090 | (0.02007, 0.1863) | |||||
ϕ 2 | 0.91 | (0.8137, 0.9799) | |||||
Cure | α | 0.845 | (0.6075, 1.1) | 341.188 | 0.503 | ||
Intercept | β 0 | 0.604 | (-0.3556, 3.394) | ||||
GCB | β 1 | -0.173 | (-0.5754, 0.2402) | ||||
Lymphoma | β 2 | -0.116 | (-0.3891, 0.1579) | ||||
Proliferation | β 3 | 0.433 | (-0.0522, 0.9041) | ||||
BMP6 | β 4 | 0.396 | (-0.0007, 0.788) | ||||
MHC | β 5 | -0.330 | (-0.6422, -0.0209) | ||||
ABC | Weibull | α | 0.894 | (0.695, 1.115) | 215.564 | 0.013 | |
Intercept | β 0 | -1.86 | (-2.562, -1.217) | ||||
GCB | β 1 | -0.509 | (-0.9948, -0.03871) | ||||
Lymphoma | β 2 | -0.626 | (-0.9568, -0.3099) | ||||
Proliferation | β 3 | -0.487 | (-1.118, 0.1422) | ||||
BMP6 | β 4 | 0.645 | (0.2725, 1.021) | ||||
MHC | β 5 | -0.479 | (-0.7955, -0.1598) | ||||
Mixture | α 1 | 2.427 | (1.083, 4.152) | 256.552 ‘ | ≈0 | ||
α 2 | 0.960 | (0.7525, 1.189) | |||||
Intercept | β 01 | 6.636 | (5.301, 7.959) | ||||
β 02 | -2.572 | (-3.346, -1.865) | |||||
GCB | β 11 | -12.11 | (-13.36, -10.86) | ||||
β 12 | -0.925 | (-1.438, -0.4356) | |||||
Lymphoma | β 21 | -3.155 | (-4.578, -1.75) | ||||
β 22 | -0.768 | (-1.114, -0.4341) | |||||
Proliferation | β 31 | -2.377 | (-3.561, -1.188) | ||||
β 32 | -0.480 | (-1.099, 0.1353) | |||||
BMP6 | β 41 | 0.079 | (-1.064, 1.232) | ||||
β 42 | 0.690 | (0.3249, 1.061) | |||||
MHC | β 51 | -0.644 | (-1.919, 0.6499) | ||||
β 52 | -0.515 | (-0.8176, -0.2047) | |||||
ϕ 1 | 0.037 | (0.0046, 0.09883) | |||||
ϕ 2 | 0.963 | (0.9012, 0.9953) | |||||
Cure | α | 1.189 | (0.8906, 1.483) | 206.961 | 0.987 | ||
Intercept | β 0 | 0.019 | (-0.6417, 0.7362) | ||||
GCB | β 1 | -0.432 | (-0.8874, 0.01376) | ||||
Lymphoma | β 2 | -0.587 | (-0.905, -0.2867) | ||||
Proliferation | β 3 | -0.484 | (-1.076, 0.1012) | ||||
BMP6 | β 4 | 0.607 | (0.2557, 0.9631) | ||||
MHC | β 5 | -0.446 | (-0.7481, -0.1346) | ||||
Type III | Weibull | α | 0.834 | (0.5958, 1.101) | 162.27 | 0.538 | |
Intercept | β 0 | -1.75 | (-2.736, -0.9093) | ||||
GCB | β 1 | -0.404 | (-1.028, -0.19) | ||||
Lymphoma | β 2 | -0.274 | (-0.7404, 0.1644) | ||||
Proliferation | β 3 | 0.506 | (-0.0897, 1.084) | ||||
BMP6 | β 4 | 0.017 | (-0.5301, 0.5206) | ||||
MHC | β 5 | -0.199 | (-0.6839, 0.3098) | ||||
Mixture | α 1 | 11.82 | (8.609, 15.14) | 196.271 | ≈0 | ||
α 2 | 0.596 | (0.43, 0.7757) | |||||
Intercept | β 01 | 6.002 | (3.682, 8.336) | ||||
β 02 | -5.005 | (-7.19, -2.812) | |||||
GCB | β 11 | -9.32 | (-12.02, -6.611) | ||||
β 12 | 0.564 | (0.1829, 1.004) | |||||
Lymphoma | β 21 | -2.913 | (-5.716, -0.02716) | ||||
β 22 | -0.558 | (-1.015, -0.1525) | |||||
Proliferation | β 31 | -2.021 | (-4.547, 0.455) | ||||
β 32 | 0.893 | (0.3455, 1.515) | |||||
BMP6 | β 41 | 0.320 | (-2.466, 3.373) | ||||
β 42 | 0.140 | (-0.2735, 0.5384) | |||||
MHC | β 51 | -0.336 | (-2.733, 2.323) | ||||
β 52 | -0.293 | (-0.7741, 0.1504) | |||||
ϕ 1 | 0.072 | (0.0108, 0.1805) | |||||
ϕ 2 | 0.928 | (0.8195, 0.9891) | |||||
Cure | α | 0.969 | (0.6534, 1.339) | 162.578 | 0.462 | ||
Intercept | β 0 | 0.989 | (-0.5077, 4.153) | ||||
GCB | β 1 | -0.349 | (-0.973, -0.25) | ||||
Lymphoma | β 2 | -0.269 | (-0.7375, 0.1687) | ||||
Proliferation | β 3 | 0.502 | (-0.0955, 1.084) | ||||
BMP6 | β 4 | 0.046 | (-0.4801, -0.1801) | ||||
MHC | β 5 | -0.183 | (-0.6625, 0.3207) |