Figure 7
Effect of sesame oil on complement system in MSU crystal-induced acute inflammation. To examine the mechanism of sesame oil-exerted anti-inflammatory effect in gout, complement system was investigated. Rats were divided into five groups of six: Group I, negative control group; Group II, rats were treated with MSU crystal (5 mg/rat); Group III-V, rats were given sesame oil 1, 2, and 4 mL/kg, respectively, 6 h after MSU crystal. Lavage C3a (A) and C5a (B) levels were assessed 12 h after MSU crystal was given. Data are means ± SD. Significant differences between groups were analyzed using one-way ANOVA. Different letters above the bars indicate significant (P < 0.05) differences.