Figure 3

Effects of sesame oil on MSU crystal-induced leukocyte and neutrophil infiltration in air pouch lavage. To investigate the effect of sesame oil on gouty inflammation, leukocyte and neutrophil infiltration number were counted. Rats were divided into five groups of six: Group I, negative control group; Group II, rats were treated with MSU crystal (5 mg/rat); Group III-V, rats were respectively given sesame oil 1, 2, and 4 mL/kg 6 h after MSU crystal. Lavage leukocyte (A) and neutrophil (B) counts were assessed 12 h after MSU crystal. The arrows indicate neutrophil in pouch lavage slides (Hematoxylin and eosin stain; magnification = ×100) (C). Data are means ± SD. Significant differences between groups were analyzed using one-way ANOVA. Different letters above the bars indicate significant (P < 0.05) differences.