Figure 2
Effect of sesame oil on MSU crystal-induced inflammatory mediator production in air pouch lavage and surrounding tissue. To examine the therapeutic potential of sesame oil on gout, cytokines were detected. Rats were divided into five groups of six: Group I, negative control group; Group II, rats were treated with MSU crystal (5 mg/rat); Group III-V, rats were respectively given sesame oil 1, 2, and 4 mL/kg 6 h after MSU crystal. TNF-α, IL-1β, and IL-6 levels in both pouch lavage (A-C) and surrounding skin tissue (D-F) were measured 12 h after MSU crystal. Data are means ± SD (n = 6). Significant differences between groups were analyzed using one way ANOVA. Different letters above the bars indicate significant (P < 0.05) differences.