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Table 4 NaOCN-induced mean numbers of carbamoylated sites (95% CI the mean response) on spinal cord proteins

From: Carbamoylation correlates of cyanate neuropathy and cyanide poisoning: relevance to the biomarkers of cassava cyanogenesis and motor system toxicity

Protein

AAA Diet

75% SAA-Deficient diet

Myelin basic protein

78.25 (70.0 - 87.4)

93 (84.0 – 102.0)

Myelin proteolipid protein

74 (66.0 – 82.9)

91.25 (82.4 – 101.0)

Neurofilament light polypeptide

48.75 (39.0 – 60.8)

67.75 (55.0 - 83.4)

Glial fibrillary acidic protein

30 (25.1 - 35.9)

40.25 (34.5 - 47.0)

2', 3' cyclic-nucleotide 3'-phosphodiesterase

6.5 (4.4 – 9.6)

18.5 (14.6 – 23.5)

  1. Carbamoylation pattern in spinal cord proteins indicates an exacerbating effect of the SAA-deficient diet, mostly for 2', 3' cyclic-nucleotide 3'-phosphodiesterase.