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Table 4 Evaluation of the introduced methodology in comparison with some of the previously reported methods

From: Macroporous polymer supported azide and nanocopper (I): efficient and reusable reagent and catalyst for multicomponent click synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from benzyl halides

Entry

Reagent/catalyst/ solvent

t (°C)

Time (h)

Yield

Reference

1

NaN3/ Silica-supported Cu(I)/ EtOH

78

24 h

93

(Miao and Wang 2008)

2

NaN3/ Silica-supported Cu(I)/ H2O

25

0.25

91

(Shamim and Paul 2010)

3

NaN3/ Nano Cu(I) on Charcol/ H2O

100

0.6

91

(Sharghi et al. 2009)

4

NaN3/ P4VPy-CuI / H2O

100

0.25

90

(Albadi et al. 2012b)

5

NaN3 / CuI/ i-Pr2EtN (additive) /[C8dabco][N(CN)2]

25

16

95

(Marra et al. 2008)

6

IRA-400 N3/ A-21CuI/ CH3CH2OH

80

1

92

(This work)