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Table 1 Synthesis of 1,4-disubstituted-1 H -1,2,3-triazoles using polymer supported reagent and catalyst

From: Macroporous polymer supported azide and nanocopper (I): efficient and reusable reagent and catalyst for multicomponent click synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from benzyl halides

Entry

Benzyl halide (a)

Product (b)

Time

Yield

m.p./Lit. m.p °C

(h)

(℅)c

1

1

92

128-129/128-129.5 (Shamim and Paul 2010)

2

1

89

 

3

1.5

83

110/ 109–110 (Sharghi et al. 2009)

4

1.5

80

117-119

5

1.5

79

140–141/ 140–142 (Shamim and Paul 2010)

6

1.5

85

147-149

7

1.5

87

152-152.5/ 151–152 (Sharghi et al. 2009)

8

1.5

75

190-192/ 191 (Sharghi et al. 2009)

9

2

79

108-110/110 (Sharghi et al. 2009)

10

1.5

83

196-198/ 197 (Sharghi et al. 2009)

11

1.5

85

197 (Sharghi et al. 2009)

12

1.5

81

139-141

13

1

74

137-139

14

1.5

70

130-131

15

1.5

79

131-133

  1. c Yields refer to isolated and pure products.