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Table 1 Synthesis of 1,4-disubstituted-1 H -1,2,3-triazoles using polymer supported reagent and catalyst

From: Macroporous polymer supported azide and nanocopper (I): efficient and reusable reagent and catalyst for multicomponent click synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from benzyl halides

Entry Benzyl halide (a) Product (b) Time Yield m.p./Lit. m.p °C
(h) (℅)c
1 1 92 128-129/128-129.5 (Shamim and Paul 2010)
2 1 89  
3 1.5 83 110/ 109–110 (Sharghi et al. 2009)
4 1.5 80 117-119
5 1.5 79 140–141/ 140–142 (Shamim and Paul 2010)
6 1.5 85 147-149
7 1.5 87 152-152.5/ 151–152 (Sharghi et al. 2009)
8 1.5 75 190-192/ 191 (Sharghi et al. 2009)
9 2 79 108-110/110 (Sharghi et al. 2009)
10 1.5 83 196-198/ 197 (Sharghi et al. 2009)
11 1.5 85 197 (Sharghi et al. 2009)
12 1.5 81 139-141
13 1 74 137-139
14 1.5 70 130-131
15 1.5 79 131-133
  1. c Yields refer to isolated and pure products.