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Table 2 Effect of UFD on oral glucose tolerance test

From: Enhanced glycemic control, pancreas protective, antioxidant and hepatoprotective effects by umbelliferon-α-D-glucopyranosyl-(2I → 1II)-α-D-glucopyranoside in streptozotocin induced diabetic rats

S. No.

Groups

Time (min)

  

0

30

60

90

120

150

1

Glucose Control

81.6 ± 1.208

154.6 ± 1.965

143.8 ± 1.158

133.2 ± 1.463

120.2 ± 1.655

110.6 ± 1.435

2

UFD (10 mg/kg)

82.4 ± 1.435

140 ± 1.517

133 ± 0.836

126.2 ± 2.289

111.4 ± 0.923

99.8 ± 0.861

3

UFD (20 mg/kg)

81.6 ± 1.077ns

130.4 ± 1.991ns

121 ± 1.817*

112 ± 1.517**

97.4 ± 0.927***

84.6 ± 1.536***

4

UFD (40 mg/kg)

82.2 ± 1.881ns

121.4 ± 1.503**

112 ± 1.517***

99.6 ± 1.208***

82 ± 2.001***

62.6 ± 1.327***

5

Glibenclamide (10 mg/kg)

81 ± 1.581ns

125 ± 0.707**

116.4 ± 0.509**

103 ± 0.717***

85.8 ± 1.158***

69.6 ± 1.248***

  1. All values represent mean ± SEM * P < 0.05; ** P < 0.01; *** P < 0.001, ns < non significant; ANOVA, followed by Dunnett’s multiple comparison test.