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Figure 19 | SpringerPlus

Figure 19

From: Enhanced glycemic control, pancreas protective, antioxidant and hepatoprotective effects by umbelliferon-α-D-glucopyranosyl-(2I → 1II)-α-D-glucopyranoside in streptozotocin induced diabetic rats

Figure 19

Effect of UFD on liver in different groups of rats: (A) Normal control: Histopathology of normal control group did not shown any fat deposition and other changes (B) Diabetic control: Histopathology of diabetic rat showed accumulation of micro droplet of fat (yellow arrow) (C) UFD I (10 mg/kg): Histopathology of the starting dose of tested drug shown some part having fat deposition which was less compared to the diabetic control (yellow arrow). (D) UFD II (20 mg/kg): Histopathology of second dose of tested drug showed very few micro droplet of fat (yellow arrow). (E) UFD III (40 mg/kg): Histopathology of other tested drug not showing any fat deposition and other changes. (F) Glibenclamide (10 mg/kg): Standard drug treated group shown histopathology similar to the normal control groups. The samples were obtained from the same liver anatomical regions. For each group, 6 rats were examined and 80 pictures were taken. The above picture for each group was chosen randomly from the 80 pictures in this group. Original magnification, 10 × .

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