Gene, chromosomal location | SNP | Genotype | Controls | Cases | P-value |
---|---|---|---|---|---|
N (%) | N (%) | ||||
FTO, 16 q12.2 | rs9939609 | A/A and A/T | 513 (71.35) | 122 (72.62) | 0.74 |
T/T | 206 (28.65) | 46 (27.38) | |||
rs1861868 | C/C and C/T | 526 (78.39) | 123 (76.88) | 0.68 | |
T/T | 145 (21.61) | 37 (23.13) | |||
rs1477196 | G/G and A/G | 582 (82.32) | 135 (82.82) | 0.88 | |
A/A | 125 (17.68) | 28 (17.18) | |||
PTGS2, 1q25.2-25.3 | rs2745559 | C/C and A/C | 632 (95.04) | 157 (96.91) | 0.31 |
A/A | 33 (4.96) | 5 (3.09) | |||
rs689466 | T/T and C/T | 483 (69.90) | 112 (69.14) | 0.85 | |
C/C | 208 (30.10) | 50 (30.86) | |||
rs689470 | G/G and A/G | 617 (86.90) | 153 (90.53) | 0.20 | |
A/A | 93 (13.10) | 16 (9.47) | |||
Rs2206593 | G/G and A/G | 602 (83.50) | 150 (86.71) | 0.30 | |
A/A | 119 (16.50) | 23 (13.29) | |||
rs5277 | C/C and C/G | 656 (97.33) | 155 (98.73) | 0.30 | |
G/G | 18 (2.67) | 2 (1.27) | |||
rs12042763 | G/G and G/T | 565 (87.73) | 134 (86.45) | 0.67 | |
T/T | 79 (12.27) | 21 (13.55) | |||
rs2383529 | A/A and A/G | 611(94.58) | 150 (96.15) | 0.42 | |
G/G | 35 (5.42) | 6 (3.85) | |||
FGGR2, 10q26 | rs1219648 | A/A and A/G | 571 (85.61) | 134 (84.28) | 0.67 |
G/G | 96 (14.39) | 25 (15.72) | |||
rs11200014 | G/G and A/G | 608 (87.11) | 131 (82.39) | 0.12 | |
A/A | 90 (12.89) | 28 (17.61) | |||
rs2981582 | G/G and A/G | 581 (85.69) | 128 (81.53) | 0.19 | |
A/A | 97 (14.31) | 29 (18.47) | |||
GHRL, 3q26.3 | rs171336 | G/G and G/T | 617 (87.64) | 148 (90.24) | 0.35 |
T/T | 87 (12.36) | 16 (9.76) | |||
rs171407 | A/A and A/G | 554 (80.06) | 128 (83.12) | 0.39 | |
G/G | 138 (19.94) | 26 (16.88) | |||
rs35684 | A/A and A/G | 663 (92.73) | 159 (95.21) | 0.25 | |
G/G | 52 (7.27) | 8 (4.79) | |||
rs4684677 | T/T and A/T | 699 (99.86) | 163 (100.00) | 0.63 | |
A/A | 1 (0.14) | 0 (0.00) | |||
rs2075356 | T/T and C/T | 629 (87.48) | 148 (91.93) | 0.11 | |
T/T | 90 (12.52) | 13 (8.07) | |||
rs27647 | T/T and C/T | 572 (82.18) | 142 (87.65) | 0.09 | |
C/C | 124 (17.82) | 20 (12.35) | |||
rs3755777 | C/C and C/G | 641 (94.40) | 152 (94.41) | 0.99 | |
G/G | 38 (5.60) | 9 (5.59) | |||
rs27498 | G/G and A/G | 604 (87.03) | 148 (88.10) | 0.71 | |
A/A | 90 (12.97) | 20 (11.90) | |||
rs10490815 | T/T and C/T | 606 (93.09) | 140 (92.72) | 0.87 | |
C/C | 45 (6.91) | 11 (7.28) | |||
GHSR, 3q26.2 | rs2948694 | A/A and A/G | 708 (98.33) | 163 (98.79) | 0.67 |
G/G | 12 (1.67) | 2 (1.21) | |||
rs2922126 | T/T and A/T | 597 (88.18) | 158 (95.18) | 0.008 1 | |
A/A | 80 (11.82) | 8 (4.82) | |||
IL6, 7p21.0 | rs4552807 | T/T and A/T | 527 (76.16) | 128 (75.74) | 0.91 |
A/A | 165 (23.84) | 41 (24.26) | |||
rs6969502 | G/G and A/G | 674 (95.33) | 158 (94.61) | 0.70 | |
A/A | 33 (4.67) | 9 (5.39) | |||
rs6952003 | T/T and A/T | 629 (94.44) | 147 (94.23) | 0.92 | |
A/A | 37 (5.56) | 9 (5.77) | |||
rs10156056 | G/G and C/G | 655 (98.05) | 153 (98.71) | 0.58 | |
C/C | 13 (1.95) | 2 (1.29) | |||
rs7776857 | T/T and G/T | 637 (88.23) | 150 (92.02) | 0.16 | |
G/G | 85 (11.77) | 13 (7.98) | |||
rs7801617 | G/G and A/G | 631 (88.50) | 158 (93.49) | 0.06 | |
A/A | 82 (11.50) | 11 (6.51) | |||
rs7805828 | A/A and A/G | 606 (87.57) | 133 (83.13) | 0.13 | |
G/G | 86 (12.43) | 27 (16.88) | |||
rs12700386 | C/C and C/G | 695 (96.80) | 161 (96.99) | 0.90 | |
G/G | 23 (3.20) | 5 (3.01) | |||
rs1800795 | C/C and G/C | 569 (81.40) | 144 (87.80) | 0.05 1 | |
G/G | 130 (18.60) | 20 (12.20) | |||
rs2069840 | C/C and C/G | 633 (90.56) | 151 (89.88) | 0.79 | |
G/G | 66 (9.44) | 17 (10.12) | |||
rs10242595 | G/G and A/G | 613 (89.75) | 143 (91.08) | 0.62 | |
A/A | 70 (10.25) | 14 (8.92) | |||
rs11766273 | G/G and A/G | 691(98.29) | 159 (100.00) | 0.097 | |
A/A | 12 (1.71) | 0 (0.00) | |||
MAP3K1, 5q11.2 | rs889312 | A/A and A/C | 679 (94.31) | 143 (86.14) | < 0.001 1 |
C/C | 41 (5.69) | 23 (13.86) | Â | ||
ESR1, 6q25.1 | rs2046210 | G/G and A/G | 573 (83.77) | 139 (84.24) | 0.88 |
A/A | 111 (16.23) | 26 (15.76) | |||
rs12662670 | T/T and G/T | 631 (92.25) | 152 (95.00) | 0.23 | |
G/G | 53 (7.75) | 8 (5.00) | |||
rs3020314 | T/T and C/T | 564 (80.34) | 134 (83.75) | 0.32 | |
C/C | 138 (19.66) | 26 (16.25) |