Table 1 Results of the use of cyproheptadine hydrochroride for in refractory migraine patients prophylaxis
From: Preventive effect of cyproheptadine hydrochloride in refractory patients with frequent migraine
n = 12 | Dose of cyproheptadine hydrocride | |
|---|---|---|
4 mg/day (n = 8) | 8 mg/day (n = 4) | |
Gender | male: female 1:7 | all female |
Average age | 34 ± 6 | 36 ± 5 |
Frequency of migraine premedication | 8.7/month | 10.6/month |
Frequency of migraine one month after start of treament | 1.6/month | 1.2/month |
Frequency of migraine three month after start of treatment | 3.1/month | 2.1/month |
Adverse reactions | Body weight 28.6% | Body weight 25.0% |
Sleepiness 14.3% | Sleepiness 50.0% | |