Skip to main content

Table 3 Comparison of L-DOPA production by biological methods

From: Statistically optimized biotransformation protocol for continuous production of L-DOPA using Mucuna monosperma callus culture

Method

Rate of production (mg l-1 h-1)

Scale (ml)

References

Mucuna pruriens single-stage culture

0.025

100

Chattopadhyay et al. (1994)

Mucuna pruriens two-stage culture

0.39

100

Chattopadhyay et al. (1994)

E. coli cloned E. herbicola culture

0.39

25

Foor et al. (1993)

Immobilized tyrosinase on nylon 6,6

1.7

500

Pialis et al. (1996)

Immobilized tyrosinase-batch reactor

1.7

500

Pialis et al. (1996)

Aspergillus oryzae (GCB-6)

7.5

100

Ali et al. (2002)

Immobilized tyrosinase batch reactor

27.6

20

Vilanova et al. (1984)

Portulaca callus cultures

48.8

100

Rani et al. (2007)

Brevundimonas sp. SGJ

186.6

100

Surwase et al. (2012b)

Pseudomonas sp. SSA

180.6

100

Patil et al. (2013)

Mucuna monosperma flask culture

19.31

50

Current study

Mucuna monosperma continuous culture

200

Continuous culture

Current study