Table 1 The Box–Behnken design matrix for coded variables along with actual and predicted responses for L-DOPA production
Std order | L-tyrosine | pH | Ascorbic acid | Copper sulphate | Actual value | Predicted value | Externally studentized residual |
|---|---|---|---|---|---|---|---|
1 | -1 | -1 | 0 | 0 | 0.082525 | 0.073007 | 1.524624 |
2 | 1 | -1 | 0 | 0 | 0.152542 | 0.146935 | 0.849911 |
3 | -1 | 1 | 0 | 0 | 0.164582 | 0.156311 | 1.296822 |
4 | 1 | 1 | 0 | 0 | 0.297604 | 0.293243 | 0.653778 |
5 | 0 | 0 | -1 | -1 | 0.193922 | 0.190677 | 0.483016 |
6 | 0 | 0 | 1 | -1 | 0.247224 | 0.241344 | 0.893731 |
7 | 0 | 0 | -1 | 1 | 0.19848 | 0.190482 | 1.24883 |
8 | 0 | 0 | 1 | 1 | 0.182934 | 0.172301 | 1.742365 |
9 | -1 | 0 | 0 | -1 | 0.185856 | 0.186702 | -0.12492 |
10 | 1 | 0 | 0 | -1 | 0.297838 | 0.30429 | -0.98693 |
11 | -1 | 0 | 0 | 1 | 0.164582 | 0.16424 | 0.050484 |
12 | 1 | 0 | 0 | 1 | 0.25225 | 0.257514 | -0.79525 |
13 | 0 | -1 | -1 | 0 | 0.056224 | 0.06576 | -1.52784 |
14 | 0 | 1 | -1 | 0 | 0.2 | 0.193774 | 0.949833 |
15 | 0 | -1 | 1 | 0 | 0.082876 | 0.095211 | -2.1082 |
16 | 0 | 1 | 1 | 0 | 0.200234 | 0.196809 | 0.510363 |
17 | -1 | 0 | -1 | 0 | 0.15 | 0.158725 | -1.37812 |
18 | 1 | 0 | -1 | 0 | 0.235885 | 0.235094 | 0.116827 |
19 | -1 | 0 | 1 | 0 | 0.137347 | 0.145906 | -1.34827 |
20 | 1 | 0 | 1 | 0 | 0.281356 | 0.280399 | 0.141305 |
21 | 0 | -1 | 0 | -1 | 0.140269 | 0.133925 | 0.969141 |
22 | 0 | 1 | 0 | -1 | 0.214611 | 0.222782 | -1.27897 |
23 | 0 | -1 | 0 | 1 | 0.073758 | 0.073356 | 0.059289 |
24 | 0 | 1 | 0 | 1 | 0.2 | 0.214112 | -2.55016 |
25 | 0 | 0 | 0 | 0 | 0.294 | 0.3012 | -0.78455 |
26 | 0 | 0 | 0 | 0 | 0.306 | 0.3012 | 0.516286 |
27 | 0 | 0 | 0 | 0 | 0.31 | 0.3012 | 0.970304 |
28 | 0 | 0 | 0 | 0 | 0.296 | 0.3012 | -0.56031 |
29 | 0 | 0 | 0 | 0 | 0.3 | 0.3012 | -0.12785 |