Human GMDS gene fragment hypermethylation in chronic high level of arsenic exposure with and without arsenic induced cancer

SpringerPlus

Table 3 Demographic data and p53 methylation status of subjects having GMDS gene hypermethylation

Sample	Age (yr)/sex	Smoking status	Conc. of arsenic in water μg/l	Duration of exposure yrs	Degree of pigmentation	Total urinary arsenic μg/l	p53 methylation value
KA 261	52/M	Non smoker	580	7	++ + 3	272.8	4.46
Gr. D	52/M	Non smoker	580	7	++ + 3	272.8	4.46
DHW 088	43/M	smoker	683	5	++++ 4	89	2.85
Gr. D	43/M	smoker	683	5	++++ 4	89	2.85
CW045	38/M	smoker	531	5	++++ 4	189	2.46
Gr.D	38/M	smoker	531	5	++++ 4	189	2.46
CNBB 33	48/F	Non-smoker	826	14	++++ 4	212	2.55
Gr.E	48/F	Non-smoker	826	14	++++ 4	212	2.55
CNBB 28	40/M	Ex smoker	740	10	++++ 4	126	1.62
Gr.E	40/M	Ex smoker	740	10	++++ 4	126	1.62
A 10	51/M	smoker	514	17	++++ ++ 6	211	3.08
Gr.E	51/M	smoker	514	17	++++ ++ 6	211	3.08
A 15	47/M	smoker	623	13	++++ ++ 6	97	2.09
Gr.E	47/M	smoker	623	13	++++ ++ 6	97	2.09
A 20	53/M	smoker	744	10	++++ 4	143	2.09
Gr.E	53/M	smoker	744	10	++++ 4	143	2.09
A 17	63/M	smoker	556	17	++++ ++ 6	171	2.20
Gr.E	63/M	smoker	556	17	++++ ++ 6	171	2.20
A 21	61/M	smoker	631	10	++++ ++ 6	206	2.23
Gr.E

Note: The pigmentation and keratosis was assigned as a numerical score according to the degree of severity.