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Table 2 Dermatological criteria and graduation of chronic arsenic toxicity for scoring sustem of skin manifestations

From: Human GMDS gene fragment hypermethylation in chronic high level of arsenic exposure with and without arsenic induced cancer

Pigmentation

  

Mild 1

Moderate score = 2

Severe score = 3

Defuse Melanosis, Mild Spotty pigmentation, Leucomelanosis

Moderate Spotty pigmentation

Blotchy Pigmentation, Pigmentation of under surface of tongue, buccal mucosa

Keratosis

  

Mild Score = 1

Moderate score = 2

Severe score = 3

Slight thickening, or minute papules (<2 cm) in palm and soles

Multiple raised keratosis papules (2 to 5 cm) in palm & soles with diffuse thickening

Diffuse severe thickening, large discreet or confluent keratotic elevations (>5 cm), palm and soles (also dorsum of extremely and trunk)

  1. The underlined data represents the clinical symptom score.