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Table 5 Clinical data and laboratory tests on patients with HRS categorized according to changes in serum sodium concentration

From: Initial serum sodium concentration determines the decrease in sodium level after terlipressin administration in patients with liver cirrhosis

Characteristics

Non-decreased (n = 24)

Decreased (n = 4)

p value

Age

53.75 ± 10.97

65.50 ± 4.93

0.006

Sex

  

0.508

 Male (%)

21 (87.5)

3 (75.0)

 

 Female (%)

3 (12.5)

1(25.0)

 

Etiology of cirrhosis

  

0.436

 Alcoholics (%)

13 (54.2)

3 (75.0)

 

 Non-alcoholics (%)

11 (45.8)

1 (25.0)

 

Infusion of albumin

  

0.436

 Yes (%)

13 (54.2)

3 (75.0)

 

 No (%)

11 (45.8)

1 (25.0)

 

Cumulative dose of Terlipressin (mg)

18.21 ± 5.92

20.25 ± 7.41

0.541

Amount of hydration (L)

3.87 ± 2.45

5.28 ± 3.21

0.317

Amount of sodium infused (mEq)

245.18 ± 242.31

207.10 ± 240.77

0.773

Total bilirubin (0 ~ 1.2 mg/dL)

16.39 ± 11.97

12.50 ± 9.93

0.545

Albumin (3.4 ~ 4.8 g/dL)

2.63 ± 0.45

2.68 ± 0.46

0.824

Creatinine (0.6 ~ 1.2 mg/dL)

3.61 ± 2.39

2.94 ± 1.56

0.617

Hemoglobin (13 ~ 17 g/dL)

10.53 ± 1.95

8.40 ± 1.12

0.045

*PT(0.8 ~ 1.2 *INR)

1.91 ± 0.63

2.88 ± 1.15

0.190

*MELD score

32.92 ± 8.87

35.50 ± 10.08

0.600

*MELD-Na

46.38 ± 15.72

32.25 ± 17.86

0.114

Child-Pugh score (6 ~ 18)

10 .79 ± 1.79

13.00 ± 0.81

0.003

Initial sodium (135 ~ 145 mmol/L)

126.50 ± 7.78

137.12 ± 5.11

0.014

Lowest sodium (135 ~ 145 mmol/L)

126.69 ± 7.44

126.98 ± 5.43

0.943

  1. * PT, Prothrombin time; INR, International normalized ratio; MELD, Model for end-stage liver disease; HRS, Hepatorenal syndrome.