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Table 4 Proportional cox regression models, n = 161,228

From: Marital status and its effect on lung cancer survival

   Model 1 Model 2 Model 3 Model 4 Model 5
Prognostic factors Category HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
Marital status Never married 1.00   1.00   1.00   1.00   1.00  
  Separated/ Divorced 1.03 (1.01, 1.05) 0.003 1.03 (0.89, 1.20) 0.654 1.03 (0.96, 1.10) 0.461 1.04 (1.01, 1.07) 0.008 1.05 (1.02, 1.08) <.001
  Widowed 0.81 (0.80, 0.83) <.001 0.82 (0.59, 1.14) 0.240 0.77 (0.63, 0.94) 0.010 0.87 (0.82, 0.91) <.001 0.88 (0.84, 0.93) <.001
  Married 0.70 (0.69, 0.71) <.001 0.71 (0.53, 0.95) 0.021 0.70 (0.60, 0.83) <.001 0.82 (0.78, 0.87) <.001 0.85 (0.81, 0.89) <.001
Race White 1.00   1.00   1.00   1.00   1.00  
  Black 1.12 (1.10, 1.14) <.001 0.97 (0.88, 1.05) 0.438 1.04 (1.01, 1.07) 0.021 0.99 (0.95, 1.02) 0.472 0.99 (0.95, 1.02) 0.391
  Other 0.91 (0.85, 0.97) 0.005 0.91 (0.85, 0.97) 0.007 1.00 (0.93, 1.08) 0.944 0.96 (0.89, 1.04) 0.314 0.85 (0.78, 0.93) <.001
Hispanic origin Non-Hispanic 1.00   1.00   1.00   1.00   1.00  
  Hispanic 0.98 (0.96, 1.01) 0.148 0.93 (0.85, 1.02) 0.130 0.97 (0.90, 1.06) 0.499 0.94 (0.89, 0.99) 0.026 0.91 (0.86, 0.96) <.001
SES Lowest 1.00   1.00   1.00   1.00   1.00  
  Middle-Low 0.90 (0.89, 0.92) <.001 0.93 (0.90, 0.97) <.001 0.95 (0.92, 0.98) <.001 0.96 (0.93, 0.98) 0.002 0.96 (0.94, 0.99) 0.005
  Middle-High 0.84 (0.83, 0.85) <.001 0.88 (0.84, 0.93) <.001 0.90 (0.86, 0.93) <.001 0.92 (0.89, 0.95) <.001 0.92 (0.90, 0.95) <.001
  Highest 0.77 (0.76, 0.79) <.001 0.82 (0.77, 0.88) <.001 0.85 (0.80, 0.91) <.001 0.88 (0.85, 0.92) <.001 0.89 (0.85, 0.92) <.001
  1. Model 1: Univariate.
  2. Model 2: Multivariate only with Marital status + Race/Ethnicity/SES.
  3. Model 3: Multivariate - Marital status + Race/Ethnicity/SES + demographics.
  4. Model 4: Multivariate - Marital status + Race/Ethnicity/SES + demographics + clinical.
  5. Model 5: Multivariate - Marital status + Race/Ethnicity/SES + demographics + clinical + individual comorbidities.
  6. Notes: there is no interaction between marital status and race, ethnicity and SES respectively.
  7. SES = Socioeconomic Status (percent living below poverty line); Lowest (≥20%); Middle-low (≥10% and <20%); Middle-high (≥5% and <10%); Highest (<5%).