| | |
Model 1
|
Model 2
|
Model 3
|
Model 4
|
Model 5
|
|---|
|
Prognostic factors
|
Category
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
P value
|
HR (95% CI)
|
P value
|
|---|
|
Marital status
|
Never married
|
1.00
| |
1.00
| |
1.00
| |
1.00
| |
1.00
| |
| |
Separated/ Divorced
|
1.03 (1.01, 1.05)
|
0.003
|
1.03 (0.89, 1.20)
|
0.654
|
1.03 (0.96, 1.10)
|
0.461
|
1.04 (1.01, 1.07)
|
0.008
|
1.05 (1.02, 1.08)
|
<.001
|
| |
Widowed
|
0.81 (0.80, 0.83)
|
<.001
|
0.82 (0.59, 1.14)
|
0.240
|
0.77 (0.63, 0.94)
|
0.010
|
0.87 (0.82, 0.91)
|
<.001
|
0.88 (0.84, 0.93)
|
<.001
|
| |
Married
|
0.70 (0.69, 0.71)
|
<.001
|
0.71 (0.53, 0.95)
|
0.021
|
0.70 (0.60, 0.83)
|
<.001
|
0.82 (0.78, 0.87)
|
<.001
|
0.85 (0.81, 0.89)
|
<.001
|
|
Race
|
White
|
1.00
| |
1.00
| |
1.00
| |
1.00
| |
1.00
| |
| |
Black
|
1.12 (1.10, 1.14)
|
<.001
|
0.97 (0.88, 1.05)
|
0.438
|
1.04 (1.01, 1.07)
|
0.021
|
0.99 (0.95, 1.02)
|
0.472
|
0.99 (0.95, 1.02)
|
0.391
|
| |
Other
|
0.91 (0.85, 0.97)
|
0.005
|
0.91 (0.85, 0.97)
|
0.007
|
1.00 (0.93, 1.08)
|
0.944
|
0.96 (0.89, 1.04)
|
0.314
|
0.85 (0.78, 0.93)
|
<.001
|
|
Hispanic origin
|
Non-Hispanic
|
1.00
| |
1.00
| |
1.00
| |
1.00
| |
1.00
| |
| |
Hispanic
|
0.98 (0.96, 1.01)
|
0.148
|
0.93 (0.85, 1.02)
|
0.130
|
0.97 (0.90, 1.06)
|
0.499
|
0.94 (0.89, 0.99)
|
0.026
|
0.91 (0.86, 0.96)
|
<.001
|
|
SES
|
Lowest
|
1.00
| |
1.00
| |
1.00
| |
1.00
| |
1.00
| |
| |
Middle-Low
|
0.90 (0.89, 0.92)
|
<.001
|
0.93 (0.90, 0.97)
|
<.001
|
0.95 (0.92, 0.98)
|
<.001
|
0.96 (0.93, 0.98)
|
0.002
|
0.96 (0.94, 0.99)
|
0.005
|
| |
Middle-High
|
0.84 (0.83, 0.85)
|
<.001
|
0.88 (0.84, 0.93)
|
<.001
|
0.90 (0.86, 0.93)
|
<.001
|
0.92 (0.89, 0.95)
|
<.001
|
0.92 (0.90, 0.95)
|
<.001
|
| |
Highest
|
0.77 (0.76, 0.79)
|
<.001
|
0.82 (0.77, 0.88)
|
<.001
|
0.85 (0.80, 0.91)
|
<.001
|
0.88 (0.85, 0.92)
|
<.001
|
0.89 (0.85, 0.92)
|
<.001
|
- Model 1: Univariate.
- Model 2: Multivariate only with Marital status + Race/Ethnicity/SES.
- Model 3: Multivariate - Marital status + Race/Ethnicity/SES + demographics.
- Model 4: Multivariate - Marital status + Race/Ethnicity/SES + demographics + clinical.
- Model 5: Multivariate - Marital status + Race/Ethnicity/SES + demographics + clinical + individual comorbidities.
- Notes: there is no interaction between marital status and race, ethnicity and SES respectively.
- SES = Socioeconomic Status (percent living below poverty line); Lowest (≥20%); Middle-low (≥10% and <20%); Middle-high (≥5% and <10%); Highest (<5%).
