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Table 2 Inhibition parameters (MIC, MBC) of methanol extract and its fractions from A. manniana leaves (mg/mL)

From: Phytochemical analysis, antimicrobial and radical-scavenging properties of Acalypha manniana leaves

 

Microorganisms

Parameters

Methanol extract

Hexane fraction

Ethyl acetate fraction

Residual fraction

Ref*

Bacteria

Salmonella typhi

MIC

0.25

2.04

0.51

0.25

0.032

MBC

4.09

8.19

4.09

1.02

0.12

MBC/MIC

8

4

8

4

4

Staphylococcus aureus

MIC

0.25

2.04

0.51

2.04

0.002

MBC

4.09

8.19

4.09

8.19

0.016

MBC/MIC

8

4

8

2

8

Pseudomonas aeruginosa

MIC

0.51

1.02

0.12

2.04

0.002

MBC

2.04

4.09

2.04

4.09

0.016

MBC/MIC

4

4

8

2

8

Escherichia coli

MIC

0.51

1.02

0.51

0.25

0.016

MBC

2.04

4.09

1.02

2.04

0.064

MBC/MIC

4

4

2

8

4

Klebsiella pneumoniae

MIC

0.51

1.02

0.51

0.51

0.008

MBC

4.09

4.09

4.09

4.09

0.016

MBC/MIC

8

4

8

8

2

Shigella flexneri

MIC

0.25

0.51

0.51

0.51

0.002

MBC

1.02

1.02

1.02

4.09

0.002

MBC/MIC

4

2

2

16

1

Enterococcus faecalis

MIC

0.25

1.02

0.51

1.02

0.001

MBC

1.02

2.04

1.02

2.04

0.001

MBC/MIC

4

2

2

2

1

Proteus mirabilis

MIC

0.51

0.51

0.51

0.51

0.001

MBC

0.51

2.04

1.02

4.09

0.001

MBC/MIC

1

4

2

8

1

Dermatophytes

Trichophyton mentagrophytes

MIC

0.25

1.02

0.51

0.51

0.01

T. equinum

MIC

0.25

0.25

0.25

0.51

0.005

T. terrestre

MIC

0.51

0.51

0.25

1.02

0.005

 

Microsporum gypseum

MIC

0.25

0.25

0.51

1.02

0.01

  1. *Ref = reference drugs: gentamycin for bacteria and griseofulvin for dermatophytes.