SCLpredT: Ab initio and homology-based prediction of subcellular localization by N-to-1 neural networks

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Table 2 Results on the BaCelLo sets

	SCLpred		BaCelLo		MSA		MSA+HOM
				Fungi
	Spec	Sens	Spec	Sens	Spec	Sens	Spec	Sens
cyto	0.46	0.39	0.39	0.60	0.74	0.30	0.72	0.34
mito	0.72	0.78	0.72	0.81	0.79	0.87	0.75	0.92
nucl	0.83	0.82	0.85	0.67	0.80	0.94	0.83	0.94
secr/extr	0.86	0.85	0.85	0.94	0.99	0.72	0.99	0.62
GC	0.67		0.66		0.69	(0.01)	0.68	(0.014)
Q	0.75		0.70		0.80	(0.008)	0.81	(0.007)
				Animals
	Spec	Sens	Spec	Sens	Spec	Sens	Spec	Sens
cyto	0.58	0.54	0.41	0.65	0.66	0.33	0.72	0.45
mito	0.77	0.74	0.66	0.76	0.68	0.93	0.69	0.98
nucl	0.83	0.85	0.85	0.65	0.77	0.92	0.83	0.92
secr/extr	0.93	0.93	0.91	0.91	0.97	0.86	0.95	0.91
GC	0.72		0.67		0.76	(0.007)	0.81	(0.006)
Q	0.82		0.74		0.80	(0.006)	0.84	(0.006)
				Plants
	Spec	Sens	Spec	Sens	Spec	Sens	Spec	Sens
chlo	0.68	0.79	0.76	0.73	0.83	0.56	0.82	0.61
cyto	0.39	0.36	0.47	0.52	0.40	0.76	0.47	0.78
mito	0.49	0.34	0.54	0.51	0.56	0.50	0.60	0.55
nucl	0.83	0.76	0.76	0.72	0.64	0.77	0.73	0.90
secr/extr	0.89	0.85	0.65	0.85	0.67	0.40	0.76	0.41
GC	0.63		0.59		0.57	(0.022)	0.66	(0.019)
Q	0.68		0.68		0.62	(0.021)	0.67	(0.019)

Results on Fungi, Animal and Plant by the MSA and MSA+HOM architectures compared against BaCelLo, measured in 10-fold cross-validation on the BaCelLo sets (see text for details). SCLpred and BaCelLo results are from (Mooney et al. 2011), Table 3. Best results are in bold. Standard deviations for MSA and MSA+HOM global results are in brackets.