Table 1 Source and description of commercial E 2 kits used to measure E 2 following aromatase inhibitor treatment
Company | Kit | Type of Assay | Sensitivity reported by manufacturer | Lowest E2Concentration on Standard Curve in our study* |
|---|---|---|---|---|
Siemens Healthcare Diagnostics (Plainfield, IL) | Immulite 2000 Estradiol | Automated Direct Chemiluminescent Immunoassay | 20 | 20 |
Siemens Healthcare Diagnostics (Plainfield, IL) | Coat-A-Count Estradiol RIA | Manual Direct RIA on coated Tube | 8 | 20 |
Siemens Healthcare Diagnostics (Plainfield, IL) | Double Antibody Estradiol RIA | Manual Direct RIA | 1.4 | 5 |
Beckman Coulter (Brea, CA) | Ultra-Sensitive Estradiol RIA | Manual Direct RIA | 2.2 | 5 |
Roche Diagnostics (Indianapolis, IN) | Elecsys 2010 Estradiol II | Automated Direct Electro-chemiluminescent Immunoassay | 5 | 5 |
Pantex Santa Monica, CA) | Extraction 125I Estradiol RIA | RIA with preceding extraction Step | 10 | 10 |