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Figure 1 | SpringerPlus

Figure 1

From: Presence of anaplastic lymphoma kinase in inflammatory breast cancer

Figure 1

Activation of ALK signaling network in pre-clinical models of IBC. Reverse Phase Protein Microarray analysis of human IBC cell lines and non-IBC human breast tumor cell lines that were cultured under low adherence conditions supporting self-renewal revealed activation of multiple members of the receptor tyrosine kinase (RTK) ALK signaling network, including JAK1/STAT3, AKT, mTor, PDK-1 and AMP kinase β. The P values for the level of phosphorylation of these signaling molecules in IBC cell lines compared with non-IBC cell lines was set at p ≤ 0.05 and the individual P values are described in the Results section.

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