Table 1 The analysis of the recommendations for amniocentesis that conducted to the discovery of the numerical chromosome abnormalities
Indications | Number of patients | Trisomy 21 | Trisomy 18 | Trisomy 13 | Monosomy X | Total aneuploidy N (%) |
|---|---|---|---|---|---|---|
Maternal serum screening positive | 50 | 2 | 1 | 0 | 1 | 4/50 (8) |
Abnormal ultrasoungraphic findings (US) | 17 | 1 | 1 | 1 | 1 | 4/17 (23.5) |
Advanced maternal age (≥ 35 years) | 16 | 2 | 0 | 0 | 0 | 2/16 (12.5) |
Family history of genetic/chromosomal disorder | 8 | 0 | 0 | 0 | 0 | 0 |
Parental anxiety | 9 | 0 | 0 | 0 | 0 | |
Total | 100 | 5 | 2 | 1 | 2 | 10 |