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Table 1 Univariate analysis between clinicopathologial characteristics and the presence of lymph node metastasis

From: Impact of tumor chronology and tumor biology on lymph node metastasis in breast cancer

Patient characteristic   Negative Positive Total P-value
   N = 1778 N = 1224 N = 3002  
Age ( mean ± SD)   57.8 ± 12.42 57.5 ± 12.48 57.7 ± 12.45  
Tumor size (mean ± SD)   22.2 ± 13.83 35.6 ± 24.33 27.7 ± 19.94  
cT (n,%) 1 1015 (57.09) 430 (35.13) 1445 (48.13) <.001
  2 683 (38.41) 636 (51.96) 1319 (43.94)  
  3 71 (3.99) 127 (10.38) 198 (6.60)  
  4 9 (0.51) 31 (2.53) 40 (1.33)  
pN (n,%) 0 1778 (100) 0 (0) 1778 (59.23) <.001
  1 0 (0) 907 (74.10) 907 (30.21)  
  2 0 (0) 211 (17.24) 211 (7.03)  
  3 0 (0) 106 (8.66) 106 (3.53)  
Tumor grade (n,%) 1 317 (17.83) 130 (10.62) 447 (14.89) <.001
  2 761 (42.80) 519 (42.40) 1280 (42.64)  
  3 700 (39.37) 575 (46.98) 1275 (42.47)  
LVI (n,%) No 1606 (90.33) 709 (57.92) 2315 (77.12) <.001
  Yes 172 (9.67) 515 (42.08) 687 (22.88)  
ER (n,%) Negative 275 (15.52) 186 (15.20) 462 (15.39) 0.807
  Positive 1502 (84.48) 1038 (84.80) 2540 (84.61)  
PR (n,%) Negative 465 (26.15) 322 (26.31) 787 (26.22) 0.925
  Positive 1313 (73.85) 902 (73.69) 2215 (73.78)  
HER-2 (n,%) Negative 1608 (90.44) 1064 (86.93) 2672 (89.01) 0.003
  Positive 170 (9.56) 160 (13.07) 330 (10.99)