Table 1 Univariate analysis between clinicopathologial characteristics and the presence of lymph node metastasis
From: Impact of tumor chronology and tumor biology on lymph node metastasis in breast cancer
Patient characteristic | Negative | Positive | Total | P-value | ||||
|---|---|---|---|---|---|---|---|---|
N = 1778 | N = 1224 | N = 3002 | ||||||
Age ( mean ± SD) | 57.8 ± 12.42 | 57.5 ± 12.48 | 57.7 ± 12.45 | |||||
Tumor size (mean ± SD) | 22.2 ± 13.83 | 35.6 ± 24.33 | 27.7 ± 19.94 | |||||
cT (n,%) | 1 | 1015 | (57.09) | 430 | (35.13) | 1445 | (48.13) | <.001 |
2 | 683 | (38.41) | 636 | (51.96) | 1319 | (43.94) | ||
3 | 71 | (3.99) | 127 | (10.38) | 198 | (6.60) | ||
4 | 9 | (0.51) | 31 | (2.53) | 40 | (1.33) | ||
pN (n,%) | 0 | 1778 | (100) | 0 | (0) | 1778 | (59.23) | <.001 |
1 | 0 | (0) | 907 | (74.10) | 907 | (30.21) | ||
2 | 0 | (0) | 211 | (17.24) | 211 | (7.03) | ||
3 | 0 | (0) | 106 | (8.66) | 106 | (3.53) | ||
Tumor grade (n,%) | 1 | 317 | (17.83) | 130 | (10.62) | 447 | (14.89) | <.001 |
2 | 761 | (42.80) | 519 | (42.40) | 1280 | (42.64) | ||
3 | 700 | (39.37) | 575 | (46.98) | 1275 | (42.47) | ||
LVI (n,%) | No | 1606 | (90.33) | 709 | (57.92) | 2315 | (77.12) | <.001 |
Yes | 172 | (9.67) | 515 | (42.08) | 687 | (22.88) | ||
ER (n,%) | Negative | 275 | (15.52) | 186 | (15.20) | 462 | (15.39) | 0.807 |
Positive | 1502 | (84.48) | 1038 | (84.80) | 2540 | (84.61) | ||
PR (n,%) | Negative | 465 | (26.15) | 322 | (26.31) | 787 | (26.22) | 0.925 |
Positive | 1313 | (73.85) | 902 | (73.69) | 2215 | (73.78) | ||
HER-2 (n,%) | Negative | 1608 | (90.44) | 1064 | (86.93) | 2672 | (89.01) | 0.003 |
Positive | 170 | (9.56) | 160 | (13.07) | 330 | (10.99) | ||