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Table 9 Independent variables and their levels for D-optimal design of the oxirane ring opening reaction

From: Synthesis and optimization ring opening of monoepoxide linoleic acid using p-toluenesulfonic acid

Independent variables

 

Variable levels

-1

0

+1

1. OA/MEOA (mol/mol)

X 1

0.2

0.4

0.6

2. PTSA/MEOA (mol/mol)

X 2

0.4

0.65

0.9

3. Temperature (°C)

X 3

90

100

110

4. Time (h)

X 4

3

4.5

6