Skip to main content

Table 1 Clinical characteristics of the patients with a secondary cancer

From: Eleven secondary cancers after hematopoietic stem cell transplantation using a total body irradiation-based regimen in 370 consecutive pediatric and adult patients

Secondary cancer

Sex

Age at TBI

Time to carcinogene sis (year)

Implant procedure

Primary tumor

State

Cause of death

Chronic GVHD

CTx regimen

Oral cavity carcinoma

F

17

15.2

allo-BMT

Lymphoma

Alive

 

-

ALL202-U

Esophageal cancer

F

39

12.2

allo-BMT

ALL

Alive

 

-

ALL202-O

Border malignant ovarian tumor

F

43

11.3

allo-BMT

ALL

Alive

 

+

ALL202-O

Thyroid papillary carcinoma

F

27

7.8

allo-PBSCT

Lymphoma

Alive

 

-

-

Both esophageal and gastric cancer

M

52

7.1

allo-BMT

MDS

Dead

Aspiration pneumonia

+

-

Head and neck cancer

M

55

3.0

allo-BMT

AML

Dead

Secondary cancer

+

IDR+AraC/HDAraC

Gastric cancer

F

17

1.9

allo-BMT

AML

Dead

Secondary cancer

+

IDR+AraC/HDAraC

Ureteral cancer

M

54

6.4

allo-BMT

MDS

Alive

 

+

-

Extragonadal germ cell tumor

M

48

3.0

allo-BMT

ALL

Dead

Secondary cancer

+

ALL202-O

Sub-maxillary gland tumor

F

29

1.4

allo-BMT

Lymphoma

Alive

 

+

-

  1. Abbreviation:TBI total body irradiation; CY cyclophosphamide; BMT bone marrow transplantation; PBSCT peripheral blood stem cell transplantation; ALL acute lymphoblastic leukemia; MDS myelodysplastic syndrome; AML acute myeloblastic leukemia.