Table 2 HLA-A single amino acid polymorphisms**
From: Lack of HLA predominance and HLA shared epitopes in biliary Atresia
Positions† | Amino acid | Patients (176) n (%) | Controls (329) n (%) | Odds Ratio | Pu value* | Pc value* |
|---|---|---|---|---|---|---|
9 | F | 134(76.14) | 251(76.29) | 1.0 | 0.97 | NS |
9 | S | 47(26.70) | 108(32.83) | 0.8 | 0.16 | NS |
9 | T | 31(17.61) | 55(16.72) | 0.9 | 0.80 | NS |
9 | Y | 70(39.77) | 123(37.39) | 0.9 | 0.60 | NS |
44 | K | 44(25.00) | 84(25.53) | 1.0 | 0.90 | NS |
56 | R | 21(11.93) | 39(11.85) | 1.0 | 0.98 | NS |
62 | E | 33(18.75) | 89(27.05) | 0.7 | 0.04 | NS |
62 | G | 82(46.59) | 160(48.63) | 1.0 | 0.66 | NS |
62 | Q | 113(64.20) | 197(59.88) | 0.9 | 0.34 | NS |
62 | R | 57(32.39) | 94(28.57) | 0.9 | 0.37 | NS |
63 | N | 57(32.39) | 94(28.57) | 0.9 | 0.37 | NS |
65 | G | 32(18.18) | 89(27.05) | 0.7 | 0.03 | NS |
66 | K | 104(59.09) | 223(67.78) | 0.9 | 0.05 | NS |
66 | N | 152(86.36) | 257(78.12) | 0.9 | 0.02 | NS |
67 | M | 44(25.00) | 84(25.53) | 1.0 | 0.90 | NS |
70 | H | 157(89.20) | 310(94.22) | 0.9 | 0.04 | NS |
70 | Q | 92(52.27) | 164(49.85) | 1.0 | 0.60 | NS |
73 | I | 20(11.36) | 37(11.25) | 1.0 | 0.97 | NS |
74 | D | 163(92.61) | 296(89.97) | 1.0 | 0.33 | NS |
74 | H | 82(46.59) | 160(48.63) | 1.0 | 0.66 | NS |
76 | A | 66(37.50) | 112(34.04) | 0.9 | 0.44 | NS |
76 | E | 55(31.25) | 119(36.17) | 0.9 | 0.27 | NS |
76 | V | 151(85.80) | 270(82.07) | 1.0 | 0.28 | NS |
77 | D | 151(85.80) | 270(82.07) | 1.0 | 0.28 | NS |
77 | N | 102(57.95) | 187(56.84) | 1.0 | 0.81 | NS |
79 | R | 46(26.14) | 111(33.74) | 0.8 | 0.08 | NS |
80 | I | 46(26.14) | 111(33.74) | 0.8 | 0.08 | NS |
81 | A | 46(26.14) | 111(33.74) | 0.8 | 0.08 | NS |
82 | L | 46(26.14) | 111(33.74) | 0.8 | 0.08 | NS |
83 | R | 46(26.14) | 111(33.74) | 0.8 | 0.08 | NS |
90 | D | 85(48.30) | 150(45.59) | 0.9 | 0.56 | NS |
95 | I | 152(86.36) | 259(78.72) | 0.9 | 0.04 | NS |
95 | L | 37(21.02) | 104(31.61) | 0.7 | 0.01 | NS |
95 | V | 76(43.18) | 145(44.07) | 1.0 | 0.85 | NS |
97 | I | 109(61.93) | 184(55.93) | 0.9 | 0.19 | NS |
97 | M | 74(42.05) | 175(53.19) | 0.8 | 0.02 | NS |
97 | R | 99(56.25) | 198(60.18) | 0.9 | 0.39 | NS |
99 | F | 32(18.18) | 89(27.05) | 0.7 | 0.03 | NS |
105 | P | 92(52.27) | 167(50.76) | 1.0 | 0.75 | NS |
105 | S | 158(89.77) | 297(90.27) | 1.0 | 0.86 | NS |
107 | G | 164(93.18) | 296(89.97) | 1.0 | 0.23 | NS |
107 | W | 82(46.59) | 161(48.94) | 1.0 | 0.62 | NS |
114 | H | 108(61.36) | 232(70.52) | 0.9 | 0.04 | NS |
114 | Q | 48(27.27) | 85(25.84) | 0.9 | 0.73 | NS |
114 | R | 109(61.93) | 193(58.66) | 0.9 | 0.48 | NS |
116 | D | 142(80.68) | 241(73.25) | 0.9 | 0.06 | NS |
116 | Y | 108(61.36) | 232(70.52) | 0.9 | 0.04 | NS |
127 | K | 115(65.34) | 250(75.99) | 0.9 | 0.01 | NS |
127 | N | 143(81.25) | 243(73.86) | 0.9 | 0.06 | NS |
142 | I | 157(89.20) | 284(86.32) | 1.0 | 0.35 | NS |
142 | T | 94(53.41) | 191(58.05) | 0.9 | 0.32 | NS |
144 | Q | 77(43.75) | 138(41.95) | 1.0 | 0.70 | NS |
145 | H | 94(53.41) | 191(58.05) | 0.9 | 0.32 | NS |
145 | R | 157(89.20) | 284(86.32) | 1.0 | 0.35 | NS |
149 | T | 28(15.91) | 41(12.46) | 0.8 | 0.28 | NS |
150 | V | 44(25.00) | 84(25.53) | 1.0 | 0.90 | NS |
151 | R | 59(33.52) | 112(34.04) | 1.0 | 0.91 | NS |
152 | A | 57(32.39) | 119(36.17) | 0.9 | 0.40 | NS |
152 | E | 65(36.93) | 96(29.18) | 0.8 | 0.07 | NS |
152 | V | 140(79.55) | 291(88.45) | 0.9 | 0.01 | NS |
156 | L | 143(81.25) | 257(78.12) | 1.0 | 0.41 | NS |
156 | Q | 40(22.73) | 101(30.70) | 0.7 | 0.06 | NS |
156 | R | 44(25.00) | 84(25.53) | 1.0 | 0.90 | NS |
156 | W | 49(27.84) | 93(28.27) | 1.0 | 0.92 | NS |
158 | V | 44(25.00) | 84(25.53) | 1.0 | 0.90 | NS |
161 | D | 44(25.00) | 56(17.02) | 0.7 | 0.03 | NS |
163 | R | 79(44.89) | 144(43.77) | 1.0 | 0.81 | NS |
166 | D | 73(41.48) | 155(47.11) | 0.9 | 0.23 | NS |
166 | E | 163(92.61) | 295(89.67) | 1.0 | 0.28 | NS |
167 | G | 73(41.48) | 155(47.11) | 0.9 | 0.23 | NS |
167 | W | 163(92.61) | 295(89.67) | 1.0 | 0.28 | NS |