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Table 3 Effect of oral administration of isolated fraction (DV-1) on plasma glucose concentration, cholesterol, triglyceride, and HDL for 21 days

From: Effect of active fraction isolated from the leaf extract of Dregea volubilis [Linn.] Benth. on plasma glucose concentration and lipid profile in streptozotocin-induced diabetic rats

Treatment Fasting plasma glucose (mg/dl) Cholesterol (mg/dl) Triglyceride (mg/dl) HDL (mg/dl)
0 day 10 day 21 day
Normal control 64.8 ± 7.9 91.9 ± 3.2 89.3 ± 6.9 93.6 ± 4.3 71.6 ± 5.6 42.2 ± 1.9
Diabetes alone 249.7 ± 4.8 207.6 ± 8.5 195.7 ± 5.4 84.5 ± 3.4 110.6 ± 7.8 40.3 ± 2.1
Diabetes + DV-1 (100 mg/kg) 252.6 ± 4.1 186.3 ± 2.5* 161.2 ± 7.1* 87.6 ± 2.6 64.6 ± 7.5* 46.7 ± 2.3*
Diabetes + Metformin (50 mg/kg) 243.6 ± 2.8 178.8 ± 4.5* 156.8 ± 6.8* 84.3 ± 4.8 95.6 ± 5.6 47.6 ± 1.3*
  1. Data are expressed as mean ± SEM. n = 6 rats per group. *p < 0.05, compared to diabetic control group.