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Table 2 Effect of different Dregea volubilis [Linn.] Benth leaf extracts on plasma glucose concentration in diabetic rats

From: Effect of active fraction isolated from the leaf extract of Dregea volubilis [Linn.] Benth. on plasma glucose concentration and lipid profile in streptozotocin-induced diabetic rats

Treatments Time (min) before and after glucose administration
−30 0 30 90 150 210
Normal animals 174.8 ± 5.6 167.8 ± 3.1 234.1 ± 2.4 225.3 ± 1.9 188.3 ± 1.8 184.2 ± 2.4
Petroleum ether (200 mg/kg) 148.5 ± 3.2 146.7 ± 4.9 237.6 ± 2.4 221.6 ± 3.4 173.7 ± 5.9 168.1 ± 1.4
Ethyl acetate (200 mg/kg) 165.9 ± 2.9 153.1 ± 4.7 229.3 ± 1.8 195.4 ± 2.4 172.4 ± 3.4 164.5 ± 4.8
Ethanol (200 mg/kg) 170.4 ± 2.6 164.4 ± 2.6 224.2 ± 1.9 180.1 ± 2.9 142.6 ± 2.3* 96.9 ± 3.6*
Metformin (50 mg/kg) 171.9 ± 3.1 170.8 ± 2.3 226.1 ± 2.5 143.4 ± 3.2* 138.9 ± 3.1* 79.8 ± 2.8*
  1. Data are expressed as mean ± SEM. n = 6 rats per group. *p < 0.05, compared to diabetic control group.