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Table 2 Effect of different Dregea volubilis [Linn.] Benth leaf extracts on plasma glucose concentration in diabetic rats

From: Effect of active fraction isolated from the leaf extract of Dregea volubilis [Linn.] Benth. on plasma glucose concentration and lipid profile in streptozotocin-induced diabetic rats

Treatments

Time (min) before and after glucose administration

−30

0

30

90

150

210

Normal animals

174.8 ± 5.6

167.8 ± 3.1

234.1 ± 2.4

225.3 ± 1.9

188.3 ± 1.8

184.2 ± 2.4

Petroleum ether (200 mg/kg)

148.5 ± 3.2

146.7 ± 4.9

237.6 ± 2.4

221.6 ± 3.4

173.7 ± 5.9

168.1 ± 1.4

Ethyl acetate (200 mg/kg)

165.9 ± 2.9

153.1 ± 4.7

229.3 ± 1.8

195.4 ± 2.4

172.4 ± 3.4

164.5 ± 4.8

Ethanol (200 mg/kg)

170.4 ± 2.6

164.4 ± 2.6

224.2 ± 1.9

180.1 ± 2.9

142.6 ± 2.3*

96.9 ± 3.6*

Metformin (50 mg/kg)

171.9 ± 3.1

170.8 ± 2.3

226.1 ± 2.5

143.4 ± 3.2*

138.9 ± 3.1*

79.8 ± 2.8*

  1. Data are expressed as mean ± SEM. n = 6 rats per group. *p < 0.05, compared to diabetic control group.