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Table 1 Effect of different Dregea volubilis [Linn.] Benth leaf extracts on plasma glucose concentration in normal rats

From: Effect of active fraction isolated from the leaf extract of Dregea volubilis [Linn.] Benth. on plasma glucose concentration and lipid profile in streptozotocin-induced diabetic rats

Treatments Time (min) before and after glucose administration
−30 0 30 90 150 210
Normal animals 78.4 ± 3.1 81.6 ± 3.1 173.2 ± 1.6 136.4 ± 1.8 99.8 ± 5.8 88.2 ± 2.4
Petroleum ether (200 mg/kg) 75.7 ± 3.2 70.5 ± 4.9 175.6 ± 2.4 114.6 ± 3.4 106.7 ± 5.9 96.1 ± 1.4
Ethyl acetate (200 mg/kg) 79.4 ± 2.9 71.4 ± 4.7 142.3 ± 1.8 117.4 ± 2.4 102.4 ± 3.4 94.5 ± 4.8
Ethanol (200 mg/kg) 76.4 ± 2.6 72.4 ± 2.6 130.2 ± 1.9 99.1 ± 2.9 92.6 ± 2.3* 84.9 ± 3.6*
Metformin (50 mg/kg) 77.9 ± 3.1 81.8 ± 2.3 124.1 ± 2.5 96.4 ± 3.2 89.9 ± 3.1* 79.8 ± 2.8*
  1. Data are expressed as mean ± SEM. n = 6 rats per group. *p < 0.05, compared to normal control group.