Effect of active fraction isolated from the leaf extract of Dregea volubilis [Linn.] Benth. on plasma glucose concentration and lipid profile in streptozotocin-induced diabetic rats

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Table 1 Effect of different Dregea volubilis [Linn.] Benth leaf extracts on plasma glucose concentration in normal rats

Treatments	Time (min) before and after glucose administration
Treatments	−30	0	30	90	150	210
Normal animals	78.4 ± 3.1	81.6 ± 3.1	173.2 ± 1.6	136.4 ± 1.8	99.8 ± 5.8	88.2 ± 2.4
Petroleum ether (200 mg/kg)	75.7 ± 3.2	70.5 ± 4.9	175.6 ± 2.4	114.6 ± 3.4	106.7 ± 5.9	96.1 ± 1.4
Ethyl acetate (200 mg/kg)	79.4 ± 2.9	71.4 ± 4.7	142.3 ± 1.8	117.4 ± 2.4	102.4 ± 3.4	94.5 ± 4.8
Ethanol (200 mg/kg)	76.4 ± 2.6	72.4 ± 2.6	130.2 ± 1.9	99.1 ± 2.9	92.6 ± 2.3*	84.9 ± 3.6*
Metformin (50 mg/kg)	77.9 ± 3.1	81.8 ± 2.3	124.1 ± 2.5	96.4 ± 3.2	89.9 ± 3.1*	79.8 ± 2.8*

Data are expressed as mean ± SEM. n = 6 rats per group. *p < 0.05, compared to normal control group.