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Table 3 Associations of hormone receptor expression with clinico-pathological features, DNA ploidy and outcome measures using two IHC methods and different cut-off values for positivity

From: Clinical relevance of the reappraisal of negative hormone receptor expression in breast cancer

Variables

ER expression

PR expression

 

(P values)

(P values)

 

Previous method

Current method

Current method

Previous method

Current method

Current method

(>10%)

(≥1%)

(>10%)

(>10%)

(≥1%)

(>10%)

Grade of differentiation

      

  G1 vs. G2+G3

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

Tumour size

      

  pT1 vs. pT2+pT3

0.017

<0.001

<0.001

0.003

<0.001

<0.001

Nodal status

      

  pN0 vs. pN1

NS

NS

NS

NS

NS

NS

DNA ploidy

      

  Diploid vs. Aneuploid

0.001

<0.001

<0.001

0.021

<0.001

0.002

Disease recurrence

      

  No vs. Yes

NS

NS

NS

0.032

NS

0.008

Death from the disease

      

  No vs. Yes

NS

NS

NS

0.010

NS

<0.001

  1. ER Estrogen receptors, PR Progesterone receptors.